BRD-K80970344_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

45 genes differentially expressed following the BRD-K80970344_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
BAG3 BCL2-associated athanogene 3
CADM1 cell adhesion molecule 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
G6PD glucose-6-phosphate dehydrogenase
GATA3 GATA binding protein 3
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GNAS GNAS complex locus
HBD hemoglobin, delta
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPB8 heat shock 22kDa protein 8
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MIR22HG MIR22 host gene
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NQO1 NAD(P)H dehydrogenase, quinone 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
TALDO1 transaldolase 1
TRIM16 tripartite motif containing 16
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ANPEP alanyl (membrane) aminopeptidase
AREG amphiregulin
CD200 CD200 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CXADR coxsackie virus and adenovirus receptor
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EREG epiregulin
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IKZF1 IKAROS family zinc finger 1 (Ikaros)
MAN1A1 mannosidase, alpha, class 1A, member 1
MARCKS myristoylated alanine-rich protein kinase C substrate
NT5E 5'-nucleotidase, ecto (CD73)
OLFM1 olfactomedin 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PROM1 prominin 1
SOX9 SRY (sex determining region Y)-box 9