BRD-K80970344_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K80970344_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
BAG3 BCL2-associated athanogene 3
BLVRB biliverdin reductase B
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
FHL2 four and a half LIM domains 2
GADD45A growth arrest and DNA-damage-inducible, alpha
GCLM glutamate-cysteine ligase, modifier subunit
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BK histone cluster 1, H2bk
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
JUN jun proto-oncogene
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP10 matrix metallopeptidase 10
MX1 MX dynamin-like GTPase 1
NQO1 NAD(P)H dehydrogenase, quinone 1
S100A9 S100 calcium binding protein A9
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
AREG amphiregulin
C6ORF62 chromosome 6 open reading frame 62
CADM1 cell adhesion molecule 1
FAM69A family with sequence similarity 69, member A
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
KLF9 Kruppel-like factor 9
LUM lumican
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAP7 microtubule-associated protein 7
MOK MOK protein kinase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRSS23 protease, serine, 23
RPS11 ribosomal protein S11
SDC4 syndecan 4
SYNM synemin, intermediate filament protein
TPD52 tumor protein D52