BRD-K80700417_SGI-1776_HT29_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-K80700417_SGI-1776_HT29_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGTR1 angiotensin II receptor, type 1
AHNAK2 AHNAK nucleoprotein 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BST2 bone marrow stromal cell antigen 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHL1 cell adhesion molecule L1-like
CLU clusterin
COBL cordon-bleu WH2 repeat protein
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXCL8 chemokine (C-X-C motif) ligand 8
DSP desmoplakin
ECI2 enoyl-CoA delta isomerase 2
FAM134C family with sequence similarity 134, member C
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GRB14 growth factor receptor-bound protein 14
GULP1 GULP, engulfment adaptor PTB domain containing 1
MT1F metallothionein 1F
MT1M metallothionein 1M
NDRG2 NDRG family member 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PEG3 paternally expressed 3
PLAC8 placenta-specific 8
RND3 Rho family GTPase 3
SCYL3 SCY1-like 3 (S. cerevisiae)
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TFPI2 tissue factor pathway inhibitor 2
TM9SF3 transmembrane 9 superfamily member 3
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHR aryl hydrocarbon receptor
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
ALOX5 arachidonate 5-lipoxygenase
ANO1 anoctamin 1, calcium activated chloride channel
ARL4C ADP-ribosylation factor-like 4C
BAX BCL2-associated X protein
BHLHE41 basic helix-loop-helix family, member e41
CD1E CD1e molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD86 CD86 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
COL8A2 collagen, type VIII, alpha 2
COLEC12 collectin sub-family member 12
CRELD2 cysteine-rich with EGF-like domains 2
CTSK cathepsin K
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPYSL2 dihydropyrimidinase-like 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IPO13 importin 13
IRAK3 interleukin-1 receptor-associated kinase 3
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KYNU kynureninase
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAN1A1 mannosidase, alpha, class 1A, member 1
MB myoglobin
MDK midkine (neurite growth-promoting factor 2)
METTL7A methyltransferase like 7A
MTSS1 metastasis suppressor 1
NCF2 neutrophil cytosolic factor 2
PAN2 PAN2 poly(A) specific ribonuclease subunit
PFKP phosphofructokinase, platelet
PTPRO protein tyrosine phosphatase, receptor type, O
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
S100A8 S100 calcium binding protein A8
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SHB Src homology 2 domain containing adaptor protein B
SULF1 sulfatase 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNS3 tensin 3
TPSAB1 tryptase alpha/beta 1