BRD-K80431395_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K80431395_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM1 absent in melanoma 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA5 annexin A5
APOD apolipoprotein D
AREG amphiregulin
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASPH aspartate beta-hydroxylase
BMP2 bone morphogenetic protein 2
BTG1 B-cell translocation gene 1, anti-proliferative
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CST3 cystatin C
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DUSP5 dual specificity phosphatase 5
EPS8 epidermal growth factor receptor pathway substrate 8
ERBB3 erb-b2 receptor tyrosine kinase 3
F3 coagulation factor III (thromboplastin, tissue factor)
GPX3 glutathione peroxidase 3
ITGA6 integrin, alpha 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBNL2 muscleblind-like splicing regulator 2
NET1 neuroepithelial cell transforming 1
PLAT plasminogen activator, tissue
PRKCD protein kinase C, delta
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SMAGP small cell adhesion glycoprotein
SOX9 SRY (sex determining region Y)-box 9
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TM4SF1 transmembrane 4 L six family member 1
TOB1 transducer of ERBB2, 1
TRIB1 tribbles pseudokinase 1
TSC22D1 TSC22 domain family, member 1

decreased expression

Symbol Name
ASS1 argininosuccinate synthase 1
BEX1 brain expressed, X-linked 1
C3ORF14 chromosome 3 open reading frame 14
CALD1 caldesmon 1
CSRP2 cysteine and glycine-rich protein 2
FAM69A family with sequence similarity 69, member A
GUSBP11 glucuronidase, beta pseudogene 11
HES1 hes family bHLH transcription factor 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
INA internexin neuronal intermediate filament protein, alpha
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
LOXL1 lysyl oxidase-like 1
LUM lumican
MEIS2 Meis homeobox 2
MOXD1 monooxygenase, DBH-like 1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PLS3 plastin 3
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRUNE2 prune homolog 2 (Drosophila)
RAB31 RAB31, member RAS oncogene family
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RRAGD Ras-related GTP binding D
SLPI secretory leukocyte peptidase inhibitor
SNX7 sorting nexin 7
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
SULF1 sulfatase 1
THBS2 thrombospondin 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TUBB2B tubulin, beta 2B class IIb
WT1 Wilms tumor 1