BRD-K79619196_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

36 genes differentially expressed following the BRD-K79619196_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ALDOC aldolase C, fructose-bisphosphate
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHIC2 cysteine-rich hydrophobic domain 2
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
DKK3 dickkopf WNT signaling pathway inhibitor 3
DUOX2 dual oxidase 2
ENO2 enolase 2 (gamma, neuronal)
HOPX HOP homeobox
IGFBP7 insulin-like growth factor binding protein 7
IL32 interleukin 32
KCNK1 potassium channel, two pore domain subfamily K, member 1
KRT7 keratin 7, type II
LGALS4 lectin, galactoside-binding, soluble, 4
NCF2 neutrophil cytosolic factor 2
NFIB nuclear factor I/B
OLFM4 olfactomedin 4
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLS1 plastin 1
PNMA2 paraneoplastic Ma antigen 2
SMAD3 SMAD family member 3
SOX9 SRY (sex determining region Y)-box 9
TFRC transferrin receptor
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
TPD52L1 tumor protein D52-like 1
YBX1 Y box binding protein 1

decreased expression

Symbol Name
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
SFRP1 secreted frizzled-related protein 1
SLC39A6 solute carrier family 39 (zinc transporter), member 6
WT1 Wilms tumor 1