BRD-K79491139_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K79491139_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG2 adhesion G protein-coupled receptor G2
AKAP12 A kinase (PRKA) anchor protein 12
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
C6ORF48 chromosome 6 open reading frame 48
CALCA calcitonin-related polypeptide alpha
COMP cartilage oligomeric matrix protein
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DACH1 dachshund family transcription factor 1
DDIT4 DNA-damage-inducible transcript 4
EDNRA endothelin receptor type A
GSTT1 glutathione S-transferase theta 1
HSPA1A heat shock 70kDa protein 1A
LCN2 lipocalin 2
MGP matrix Gla protein
MXRA5 matrix-remodelling associated 5
NEBL nebulette
PGLS 6-phosphogluconolactonase
PHGDH phosphoglycerate dehydrogenase
PHYH phytanoyl-CoA 2-hydroxylase
SCG5 secretogranin V
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
THBS4 thrombospondin 4
TSC22D3 TSC22 domain family, member 3
TSKU tsukushi, small leucine rich proteoglycan

decreased expression

Symbol Name
ADM adrenomedullin
AQP3 aquaporin 3 (Gill blood group)
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATAD2 ATPase family, AAA domain containing 2
CA2 carbonic anhydrase II
CCL19 chemokine (C-C motif) ligand 19
CCNA2 cyclin A2
CD58 CD58 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDK1 cyclin-dependent kinase 1
CLCA2 chloride channel accessory 2
CXCL14 chemokine (C-X-C motif) ligand 14
DST dystonin
ETNK1 ethanolamine kinase 1
GJA1 gap junction protein, alpha 1, 43kDa
H2AFX H2A histone family, member X
HIST1H1C histone cluster 1, H1c
HIST1H2BK histone cluster 1, H2bk
JCHAIN joining chain of multimeric IgA and IgM
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LTF lactotransferrin
RRM2 ribonucleotide reductase M2
S100A7 S100 calcium binding protein A7
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPRR1B small proline-rich protein 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative)
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF395 zinc finger protein 395
ZWINT ZW10 interacting kinetochore protein