BRD-K79425933_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

120 genes differentially expressed following the BRD-K79425933_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACKR3 atypical chemokine receptor 3
ACOT9 acyl-CoA thioesterase 9
AHNAK2 AHNAK nucleoprotein 2
ANXA3 annexin A3
AREG amphiregulin
AXL AXL receptor tyrosine kinase
CAB39 calcium binding protein 39
CD24 CD24 molecule
CD58 CD58 molecule
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CRCT1 cysteine-rich C-terminal 1
CREM cAMP responsive element modulator
CRY1 cryptochrome circadian clock 1
CXCL14 chemokine (C-X-C motif) ligand 14
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHCR7 7-dehydrocholesterol reductase
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP14 dual specificity phosphatase 14
DUSP5 dual specificity phosphatase 5
EMP1 epithelial membrane protein 1
EPCAM epithelial cell adhesion molecule
EPHA2 EPH receptor A2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EZR ezrin
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
FGFBP1 fibroblast growth factor binding protein 1
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
FOSL2 FOS-like antigen 2
FOXO3 forkhead box O3
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBEGF heparin-binding EGF-like growth factor
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IFI27 interferon, alpha-inducible protein 27
ILK integrin-linked kinase
INHBB inhibin, beta B
JUN jun proto-oncogene
JUND jun D proto-oncogene
KLF6 Kruppel-like factor 6
KRT16 keratin 16, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
LDLR low density lipoprotein receptor
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCL1 myeloid cell leukemia 1
MIR22HG MIR22 host gene
MSMO1 methylsterol monooxygenase 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NPC1 Niemann-Pick disease, type C1
PALLD palladin, cytoskeletal associated protein
PDLIM5 PDZ and LIM domain 5
PHLDA1 pleckstrin homology-like domain, family A, member 1
PI3 peptidase inhibitor 3, skin-derived
PLAU plasminogen activator, urokinase
PPARD peroxisome proliferator-activated receptor delta
PRSS23 protease, serine, 23
PSME4 proteasome (prosome, macropain) activator subunit 4
PTHLH parathyroid hormone-like hormone
RHOB ras homolog family member B
RHOD ras homolog family member D
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A2 S100 calcium binding protein A2
SAMD4A sterile alpha motif domain containing 4A
SFN stratifin
SMS spermine synthase
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR2B small proline-rich protein 2B
SPRR3 small proline-rich protein 3
SPTAN1 spectrin, alpha, non-erythrocytic 1
TACSTD2 tumor-associated calcium signal transducer 2
TIMP3 TIMP metallopeptidase inhibitor 3
TJP1 tight junction protein 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TPM1 tropomyosin 1 (alpha)
TRIO trio Rho guanine nucleotide exchange factor
TSC22D2 TSC22 domain family, member 2
TUBB2A tubulin, beta 2A class IIa
TUFT1 tuftelin 1
ZYX zyxin

decreased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALOX5 arachidonate 5-lipoxygenase
ARID5B AT rich interactive domain 5B (MRF1-like)
BHLHE41 basic helix-loop-helix family, member e41
CA12 carbonic anhydrase XII
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL3A1 collagen, type III, alpha 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DPYD dihydropyrimidine dehydrogenase
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GATA2 GATA binding protein 2
GSDMB gasdermin B
HBB hemoglobin, beta
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOXA10 homeobox A10
HOXD1 homeobox D1
ITM2A integral membrane protein 2A
JCHAIN joining chain of multimeric IgA and IgM
KIF20A kinesin family member 20A
LY6E lymphocyte antigen 6 complex, locus E
MDFIC MyoD family inhibitor domain containing
MYRF myelin regulatory factor
NQO1 NAD(P)H dehydrogenase, quinone 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
ST18 suppression of tumorigenicity 18, zinc finger
TPBG trophoblast glycoprotein
TRIB2 tribbles pseudokinase 2
TSPAN8 tetraspanin 8
WNT5A wingless-type MMTV integration site family, member 5A