BRD-K79425933_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K79425933_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ARG2 arginase 2
CADM1 cell adhesion molecule 1
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD9 CD9 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL13A1 collagen, type XIII, alpha 1
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP1 dual specificity phosphatase 1
DUSP5 dual specificity phosphatase 5
EDNRA endothelin receptor type A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
GLIPR1 GLI pathogenesis-related 1
GOLM1 golgi membrane protein 1
HOPX HOP homeobox
HSPA8 heat shock 70kDa protein 8
IGFBP7 insulin-like growth factor binding protein 7
KIF5C kinesin family member 5C
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MLPH melanophilin
MMP7 matrix metallopeptidase 7
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYOF myoferlin
NAV2 neuron navigator 2
NRIP1 nuclear receptor interacting protein 1
NXN nucleoredoxin
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PDGFC platelet derived growth factor C
PHLDA1 pleckstrin homology-like domain, family A, member 1
PPL periplakin
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RHOB ras homolog family member B
RIN2 Ras and Rab interactor 2
SAMD4A sterile alpha motif domain containing 4A
SCG5 secretogranin V
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFN stratifin
STK39 serine threonine kinase 39
TACSTD2 tumor-associated calcium signal transducer 2
THBS1 thrombospondin 1
TM4SF1 transmembrane 4 L six family member 1
TMC5 transmembrane channel-like 5
UBE2D1 ubiquitin-conjugating enzyme E2D 1
VNN1 vanin 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
CA2 carbonic anhydrase II
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CPA3 carboxypeptidase A3 (mast cell)
CYBA cytochrome b-245, alpha polypeptide
ELP5 elongator acetyltransferase complex subunit 5
GRB14 growth factor receptor-bound protein 14
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HOXC6 homeobox C6
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
MARCKS myristoylated alanine-rich protein kinase C substrate
NDRG2 NDRG family member 2
PLK1 polo-like kinase 1
PUF60 poly-U binding splicing factor 60KDa
RHOBTB3 Rho-related BTB domain containing 3
S100P S100 calcium binding protein P
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SPON1 spondin 1, extracellular matrix protein
TMEM47 transmembrane protein 47
VCAM1 vascular cell adhesion molecule 1
WWOX WW domain containing oxidoreductase