BRD-K79404599_HY-10342_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

36 genes differentially expressed following the BRD-K79404599_HY-10342_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
CXCL13 chemokine (C-X-C motif) ligand 13
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EGR1 early growth response 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
IGHMBP2 immunoglobulin mu binding protein 2
IGKV3-20 immunoglobulin kappa variable 3-20
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
KIAA0226L KIAA0226-like

decreased expression

Symbol Name
AOX1 aldehyde oxidase 1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CA2 carbonic anhydrase II
CARHSP1 calcium regulated heat stable protein 1, 24kDa
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP6 dual specificity phosphatase 6
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EPS8 epidermal growth factor receptor pathway substrate 8
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GPX1 glutathione peroxidase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
JADE2 jade family PHD finger 2
LMO2 LIM domain only 2 (rhombotin-like 1)
PDZK1 PDZ domain containing 1
PODXL podocalyxin-like
RHOBTB3 Rho-related BTB domain containing 3
SMAD3 SMAD family member 3
SOX4 SRY (sex determining region Y)-box 4
TFF1 trefoil factor 1
TSPAN8 tetraspanin 8
VCAN versican