BRD-K79390395_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K79390395_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADORA2B adenosine A2b receptor
BLNK B-cell linker
C1ORF106 chromosome 1 open reading frame 106
DUSP2 dual specificity phosphatase 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
HACD1 3-hydroxyacyl-CoA dehydratase 1
HMOX1 heme oxygenase 1
LEFTY1 left-right determination factor 1
LGALS3 lectin, galactoside-binding, soluble, 3
NEBL nebulette
NLGN4X neuroligin 4, X-linked
PEG3 paternally expressed 3
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PTN pleiotrophin
S100P S100 calcium binding protein P
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SORD sorbitol dehydrogenase

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
CKS2 CDC28 protein kinase regulatory subunit 2
COMMD8 COMM domain containing 8
CYR61 cysteine-rich, angiogenic inducer, 61
FADS1 fatty acid desaturase 1
JCHAIN joining chain of multimeric IgA and IgM
MAPT microtubule-associated protein tau
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
POSTN periostin, osteoblast specific factor
RHOB ras homolog family member B
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1