BRD-K79353516_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K79353516_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANGPTL2 angiopoietin-like 2
BMP2 bone morphogenetic protein 2
BTG2 BTG family, member 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
COL16A1 collagen, type XVI, alpha 1
CTSH cathepsin H
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GCLC glutamate-cysteine ligase, catalytic subunit
GSTM3 glutathione S-transferase mu 3 (brain)
HMOX1 heme oxygenase 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP3 insulin-like growth factor binding protein 3
JAG1 jagged 1
L1CAM L1 cell adhesion molecule
LAMB3 laminin, beta 3
MAOA monoamine oxidase A
MTSS1 metastasis suppressor 1
MYL9 myosin, light chain 9, regulatory
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
RAP1GAP RAP1 GTPase activating protein
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SESN1 sestrin 1
SIK1 salt-inducible kinase 1
SNAI2 snail family zinc finger 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THBD thrombomodulin
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSKU tsukushi, small leucine rich proteoglycan
TSPAN7 tetraspanin 7
TXNRD1 thioredoxin reductase 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CA2 carbonic anhydrase II
CANT1 calcium activated nucleotidase 1
CCNA2 cyclin A2
CD36 CD36 molecule (thrombospondin receptor)
CD52 CD52 molecule
CDK1 cyclin-dependent kinase 1
CENPF centromere protein F, 350/400kDa
CEP55 centrosomal protein 55kDa
CKS2 CDC28 protein kinase regulatory subunit 2
EVL Enah/Vasp-like
GADD45B growth arrest and DNA-damage-inducible, beta
HIST1H4C histone cluster 1, H4c
HOXB2 homeobox B2
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MALL mal, T-cell differentiation protein-like
MKI67 marker of proliferation Ki-67
NEK2 NIMA-related kinase 2
NPY1R neuropeptide Y receptor Y1
PLK1 polo-like kinase 1
PODXL podocalyxin-like
RTN1 reticulon 1
TACC3 transforming, acidic coiled-coil containing protein 3