BRD-K79259477_KIN001-265_HT29_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

109 genes differentially expressed following the BRD-K79259477_KIN001-265_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
BLNK B-cell linker
BPHL biphenyl hydrolase-like (serine hydrolase)
C1ORF115 chromosome 1 open reading frame 115
CASP7 caspase 7, apoptosis-related cysteine peptidase
CAST calpastatin
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CFB complement factor B
CKB creatine kinase, brain
CLCA1 chloride channel accessory 1
CXCL14 chemokine (C-X-C motif) ligand 14
DDAH2 dimethylarginine dimethylaminohydrolase 2
DEFB1 defensin, beta 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EZR ezrin
FCGBP Fc fragment of IgG binding protein
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
GMPR guanosine monophosphate reductase
GPR143 G protein-coupled receptor 143
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ITFG1 integrin alpha FG-GAP repeat containing 1
ITM2C integral membrane protein 2C
KIAA0226L KIAA0226-like
LEFTY1 left-right determination factor 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MID1 midline 1
MME membrane metallo-endopeptidase
MMP12 matrix metallopeptidase 12
MUC4 mucin 4, cell surface associated
OLFM4 olfactomedin 4
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PRAME preferentially expressed antigen in melanoma
QPRT quinolinate phosphoribosyltransferase
RAB40B RAB40B, member RAS oncogene family
SELENBP1 selenium binding protein 1
SOX4 SRY (sex determining region Y)-box 4
SPINK4 serine peptidase inhibitor, Kazal type 4
SPON2 spondin 2, extracellular matrix protein
TMC5 transmembrane channel-like 5
TMPRSS4 transmembrane protease, serine 4
TRAF5 TNF receptor-associated factor 5
TRIM2 tripartite motif containing 2
TST thiosulfate sulfurtransferase (rhodanese)
TUBA1A tubulin, alpha 1a
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDOA aldolase A, fructose-bisphosphate
ANXA1 annexin A1
AREG amphiregulin
CAV1 caveolin 1, caveolae protein, 22kDa
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSTA cystatin A (stefin A)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EGR1 early growth response 1
EGR2 early growth response 2
ENO1 enolase 1, (alpha)
EREG epiregulin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FLNA filamin A, alpha
FOSL1 FOS-like antigen 1
GATA3 GATA binding protein 3
GPX3 glutathione peroxidase 3
HBEGF heparin-binding EGF-like growth factor
HK2 hexokinase 2
IFRD2 interferon-related developmental regulator 2
IGFBP6 insulin-like growth factor binding protein 6
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT7 keratin 7, type II
LTF lactotransferrin
MAP1B microtubule-associated protein 1B
MGP matrix Gla protein
MYBPC1 myosin binding protein C, slow type
NQO1 NAD(P)H dehydrogenase, quinone 1
ODC1 ornithine decarboxylase 1
PCNA proliferating cell nuclear antigen
PDLIM3 PDZ and LIM domain 3
PFKP phosphofructokinase, platelet
PGAM1 phosphoglycerate mutase 1 (brain)
POSTN periostin, osteoblast specific factor
PRKCH protein kinase C, eta
PRMT1 protein arginine methyltransferase 1
PRNP prion protein
PTGIS prostaglandin I2 (prostacyclin) synthase
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RGS2 regulator of G-protein signaling 2
RPS11 ribosomal protein S11
SCGB2A2 secretoglobin, family 2A, member 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIK1 salt-inducible kinase 1
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SRM spermidine synthase
SVIL supervillin
SYNM synemin, intermediate filament protein
TAGLN transgelin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFA transforming growth factor, alpha