BRD-K79131428_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K79131428_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BAG3 BCL2-associated athanogene 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLU clusterin
CST3 cystatin C
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
GCH1 GTP cyclohydrolase 1
GLRX glutaredoxin (thioltransferase)
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
LIPG lipase, endothelial
LPIN1 lipin 1
MANF mesencephalic astrocyte-derived neurotrophic factor
MSMO1 methylsterol monooxygenase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
PDIA6 protein disulfide isomerase family A, member 6
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
TOB1 transducer of ERBB2, 1
TXNIP thioredoxin interacting protein
WIPI1 WD repeat domain, phosphoinositide interacting 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
CLEC2B C-type lectin domain family 2, member B
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
GJA1 gap junction protein, alpha 1, 43kDa
GPNMB glycoprotein (transmembrane) nmb
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOX3 TOX high mobility group box family member 3
TUBB2A tubulin, beta 2A class IIa