BRD-K79131256_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

104 genes differentially expressed following the BRD-K79131256_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACOT9 acyl-CoA thioesterase 9
AGR2 anterior gradient 2
AHR aryl hydrocarbon receptor
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AMD1 adenosylmethionine decarboxylase 1
CAB39 calcium binding protein 39
CBX1 chromobox homolog 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHL1 cell adhesion molecule L1-like
COL5A2 collagen, type V, alpha 2
CTGF connective tissue growth factor
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CXCL14 chemokine (C-X-C motif) ligand 14
DHRS9 dehydrogenase/reductase (SDR family) member 9
ECM1 extracellular matrix protein 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EMP1 epithelial membrane protein 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM134B family with sequence similarity 134, member B
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GMDS GDP-mannose 4,6-dehydratase
GPRC5A G protein-coupled receptor, class C, group 5, member A
HEPH hephaestin
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXB6 homeobox B6
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
ILK integrin-linked kinase
KLF10 Kruppel-like factor 10
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP7 microtubule-associated protein 7
MARCKS myristoylated alanine-rich protein kinase C substrate
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MUC4 mucin 4, cell surface associated
NOTCH2 notch 2
PALLD palladin, cytoskeletal associated protein
PDGFA platelet-derived growth factor alpha polypeptide
PDGFD platelet derived growth factor D
PLS1 plastin 1
PLXNC1 plexin C1
PROM1 prominin 1
PRSS2 protease, serine, 2 (trypsin 2)
PRSS3 protease, serine, 3
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RCAN1 regulator of calcineurin 1
SCG5 secretogranin V
SFN stratifin
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SMS spermine synthase
SNX11 sorting nexin 11
SPATA2L spermatogenesis associated 2-like
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPOP speckle-type POZ protein
SPTAN1 spectrin, alpha, non-erythrocytic 1
SUN1 Sad1 and UNC84 domain containing 1
TFF1 trefoil factor 1
TMEM14A transmembrane protein 14A
TMEM176B transmembrane protein 176B
TOB1 transducer of ERBB2, 1
TPM1 tropomyosin 1 (alpha)

decreased expression

Symbol Name
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BTG2 BTG family, member 2
CA2 carbonic anhydrase II
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLC Charcot-Leyden crystal galectin
DHRS2 dehydrogenase/reductase (SDR family) member 2
EIF5A eukaryotic translation initiation factor 5A
FABP4 fatty acid binding protein 4, adipocyte
FUS FUS RNA binding protein
G0S2 G0/G1 switch 2
GATA2 GATA binding protein 2
GJA1 gap junction protein, alpha 1, 43kDa
HCAR3 hydroxycarboxylic acid receptor 3
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HP haptoglobin
KRT23 keratin 23, type I
MAOB monoamine oxidase B
MMP9 matrix metallopeptidase 9
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
NCAM1 neural cell adhesion molecule 1
OBSL1 obscurin-like 1
PDIA3 protein disulfide isomerase family A, member 3
PEG10 paternally expressed 10
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RGCC regulator of cell cycle
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SOD2 superoxide dismutase 2, mitochondrial
TFPI2 tissue factor pathway inhibitor 2
TMSB15A thymosin beta 15a
VEGFA vascular endothelial growth factor A
VTCN1 V-set domain containing T cell activation inhibitor 1
WNT5A wingless-type MMTV integration site family, member 5A
XIST X inactive specific transcript (non-protein coding)