BRD-K79124250_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K79124250_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CHRDL1 chordin-like 1
CXADR coxsackie virus and adenovirus receptor
EPHA3 EPH receptor A3
HNMT histamine N-methyltransferase
PERP PERP, TP53 apoptosis effector
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PPL periplakin
RIN2 Ras and Rab interactor 2
RND3 Rho family GTPase 3
RNF167 ring finger protein 167
S100A12 S100 calcium binding protein A12
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
STX1A syntaxin 1A (brain)
SYT1 synaptotagmin I
TACSTD2 tumor-associated calcium signal transducer 2
TBX3 T-box 3
TRIB2 tribbles pseudokinase 2

decreased expression

Symbol Name
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
COL6A2 collagen, type VI, alpha 2
CPE carboxypeptidase E
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
CYTL1 cytokine-like 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FCGBP Fc fragment of IgG binding protein
GLIPR1 GLI pathogenesis-related 1
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
KRT20 keratin 20, type I
LYZ lysozyme
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MMP9 matrix metallopeptidase 9
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PRKD3 protein kinase D3
RCAN1 regulator of calcineurin 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TFF3 trefoil factor 3 (intestinal)
TSPAN7 tetraspanin 7