BRD-K79092138_NITROFURAZONE_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

100 genes differentially expressed following the BRD-K79092138_NITROFURAZONE_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK2 AHNAK nucleoprotein 2
AKAP12 A kinase (PRKA) anchor protein 12
ATP10A ATPase, class V, type 10A
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD24 CD24 molecule
CELF2 CUGBP, Elav-like family member 2
CEP350 centrosomal protein 350kDa
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COMP cartilage oligomeric matrix protein
CTSB cathepsin B
DACT1 dishevelled-binding antagonist of beta-catenin 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
DMD dystrophin
EFS embryonal Fyn-associated substrate
FABP7 fatty acid binding protein 7, brain
FN1 fibronectin 1
HBB hemoglobin, beta
HDGFRP3 hepatoma-derived growth factor, related protein 3
HIST1H2BG histone cluster 1, H2bg
IFITM1 interferon induced transmembrane protein 1
KIAA0125 KIAA0125
KIAA0226L KIAA0226-like
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LRRC15 leucine rich repeat containing 15
LRRN3 leucine rich repeat neuronal 3
MFAP5 microfibrillar associated protein 5
MMP10 matrix metallopeptidase 10
NID2 nidogen 2 (osteonidogen)
NOV nephroblastoma overexpressed
NR4A2 nuclear receptor subfamily 4, group A, member 2
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
RAB31 RAB31, member RAS oncogene family
SELL selectin L
SERINC5 serine incorporator 5
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYNE1 spectrin repeat containing, nuclear envelope 1
TGFBI transforming growth factor, beta-induced, 68kDa
TIAM1 T-cell lymphoma invasion and metastasis 1
TLR7 toll-like receptor 7
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ACAT2 acetyl-CoA acetyltransferase 2
ADI1 acireductone dioxygenase 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ANXA4 annexin A4
ASRGL1 asparaginase like 1
CA2 carbonic anhydrase II
CCNB1 cyclin B1
CDC25B cell division cycle 25B
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CNIH4 cornichon family AMPA receptor auxiliary protein 4
CTNND1 catenin (cadherin-associated protein), delta 1
CTSA cathepsin A
CXCL14 chemokine (C-X-C motif) ligand 14
CYB5A cytochrome b5 type A (microsomal)
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNM1L dynamin 1-like
DUSP6 dual specificity phosphatase 6
ENO1 enolase 1, (alpha)
ENOPH1 enolase-phosphatase 1
FABP4 fatty acid binding protein 4, adipocyte
FAM60A family with sequence similarity 60, member A
HAT1 histone acetyltransferase 1
HMGA1 high mobility group AT-hook 1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HPCAL1 hippocalcin-like 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
ITGA6 integrin, alpha 6
LAP3 leucine aminopeptidase 3
LYZ lysozyme
MFSD10 major facilitator superfamily domain containing 10
MMP7 matrix metallopeptidase 7
MRPS35 mitochondrial ribosomal protein S35
NOP16 NOP16 nucleolar protein
OSBPL1A oxysterol binding protein-like 1A
PDZK1IP1 PDZK1 interacting protein 1
PLBD1 phospholipase B domain containing 1
PPA2 pyrophosphatase (inorganic) 2
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC35F2 solute carrier family 35, member F2
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRY2 sprouty homolog 2 (Drosophila)
STIP1 stress-induced phosphoprotein 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SYPL1 synaptophysin-like 1
TM4SF1 transmembrane 4 L six family member 1
TOX3 TOX high mobility group box family member 3
TRIM2 tripartite motif containing 2
TXNL4A thioredoxin-like 4A