BRD-K79090631_CGP-60474_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

116 genes differentially expressed following the BRD-K79090631_CGP-60474_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADRB2 adrenoceptor beta 2, surface
AKAP7 A kinase (PRKA) anchor protein 7
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANXA5 annexin A5
APOB apolipoprotein B
APOD apolipoprotein D
BLNK B-cell linker
C4BPA complement component 4 binding protein, alpha
CCL20 chemokine (C-C motif) ligand 20
CDK2AP1 cyclin-dependent kinase 2 associated protein 1
CLU clusterin
COL4A2 collagen, type IV, alpha 2
COL6A2 collagen, type VI, alpha 2
COL6A3 collagen, type VI, alpha 3
COMP cartilage oligomeric matrix protein
CP ceruloplasmin (ferroxidase)
CSTA cystatin A (stefin A)
CYFIP2 cytoplasmic FMR1 interacting protein 2
DLK1 delta-like 1 homolog (Drosophila)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ELN elastin
FHL1 four and a half LIM domains 1
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOLR1 folate receptor 1 (adult)
GLUL glutamate-ammonia ligase
GSN gelsolin
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGL immunoglobulin lambda locus
INPP5F inositol polyphosphate-5-phosphatase F
KIAA0226L KIAA0226-like
LEF1 lymphoid enhancer-binding factor 1
LIMA1 LIM domain and actin binding 1
LPCAT1 lysophosphatidylcholine acyltransferase 1
MAGED1 melanoma antigen family D1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MGP matrix Gla protein
NDRG2 NDRG family member 2
NEFL neurofilament, light polypeptide
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAM peptidylglycine alpha-amidating monooxygenase
PBLD phenazine biosynthesis-like protein domain containing
PCOLCE2 procollagen C-endopeptidase enhancer 2
PLBD1 phospholipase B domain containing 1
POSTN periostin, osteoblast specific factor
PTGDS prostaglandin D2 synthase 21kDa (brain)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SH3YL1 SH3 and SYLF domain containing 1
SPINK1 serine peptidase inhibitor, Kazal type 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP3 TIMP metallopeptidase inhibitor 3
TSPAN13 tetraspanin 13

decreased expression

Symbol Name
ACP5 acid phosphatase 5, tartrate resistant
ADM adrenomedullin
AQP3 aquaporin 3 (Gill blood group)
ATF3 activating transcription factor 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BAMBI BMP and activin membrane-bound inhibitor
BTG2 BTG family, member 2
C1ORF116 chromosome 1 open reading frame 116
C1QB complement component 1, q subcomponent, B chain
CCNE2 cyclin E2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
COL11A1 collagen, type XI, alpha 1
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
EFNA1 ephrin-A1
EGFR epidermal growth factor receptor
FOSL1 FOS-like antigen 1
FOXO1 forkhead box O1
GADD45A growth arrest and DNA-damage-inducible, alpha
GATA3 GATA binding protein 3
GCLM glutamate-cysteine ligase, modifier subunit
GREM1 gremlin 1, DAN family BMP antagonist
HEXIM1 hexamethylene bis-acetamide inducible 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER2 immediate early response 2
IER3 immediate early response 3
IER5 immediate early response 5
INHBB inhibin, beta B
JUNB jun B proto-oncogene
KLF5 Kruppel-like factor 5 (intestinal)
KRT15 keratin 15, type I
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KRT7 keratin 7, type II
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP7 microtubule-associated protein 7
MCL1 myeloid cell leukemia 1
MMP12 matrix metallopeptidase 12
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
RGS1 regulator of G-protein signaling 1
RND3 Rho family GTPase 3
RPL37A ribosomal protein L37a
SATB2 SATB homeobox 2
SFN stratifin
SIK1 salt-inducible kinase 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
SPEN spen family transcriptional repressor
TACSTD2 tumor-associated calcium signal transducer 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
WEE1 WEE1 G2 checkpoint kinase
ZFP36 ZFP36 ring finger protein