BRD-K79090631_CGP-60474_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

114 genes differentially expressed following the BRD-K79090631_CGP-60474_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK4 adenylate kinase 4
ALCAM activated leukocyte cell adhesion molecule
BCHE butyrylcholinesterase
CD164 CD164 molecule, sialomucin
CHRDL1 chordin-like 1
DES desmin
DNTT DNA nucleotidylexotransferase
ENO1 enolase 1, (alpha)
FKBP1A FK506 binding protein 1A, 12kDa
FLNA filamin A, alpha
FOLR1 folate receptor 1 (adult)
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPM6A glycoprotein M6A
GSTP1 glutathione S-transferase pi 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HOPX HOP homeobox
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGL immunoglobulin lambda locus
ITM2A integral membrane protein 2A
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LBH limb bud and heart development
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LTA4H leukotriene A4 hydrolase
MACF1 microtubule-actin crosslinking factor 1
MAOA monoamine oxidase A
METTL7A methyltransferase like 7A
MUC16 mucin 16, cell surface associated
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NLRP2 NLR family, pyrin domain containing 2
NREP neuronal regeneration related protein
OSMR oncostatin M receptor
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1
PBX3 pre-B-cell leukemia homeobox 3
PDGFC platelet derived growth factor C
PGK1 phosphoglycerate kinase 1
PRKCB protein kinase C, beta
RFX5 regulatory factor X, 5 (influences HLA class II expression)
S100A4 S100 calcium binding protein A4
SCGB2A1 secretoglobin, family 2A, member 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
STEAP1 six transmembrane epithelial antigen of the prostate 1
TCF4 transcription factor 4
TNS3 tensin 3
TSPAN13 tetraspanin 13
TSPAN8 tetraspanin 8
VIM vimentin

decreased expression

Symbol Name
APOLD1 apolipoprotein L domain containing 1
ARID4B AT rich interactive domain 4B (RBP1-like)
BAMBI BMP and activin membrane-bound inhibitor
BTG2 BTG family, member 2
CBR3 carbonyl reductase 3
CCNE2 cyclin E2
CD14 CD14 molecule
CD24 CD24 molecule
CDC25A cell division cycle 25A
CDCA4 cell division cycle associated 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CHD1 chromodomain helicase DNA binding protein 1
CTGF connective tissue growth factor
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP4 dual specificity phosphatase 4
EGR3 early growth response 3
EIF5 eukaryotic translation initiation factor 5
ESR1 estrogen receptor 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP7 fatty acid binding protein 7, brain
FOSL1 FOS-like antigen 1
FOXO1 forkhead box O1
FZD7 frizzled class receptor 7
GADD45B growth arrest and DNA-damage-inducible, beta
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GEM GTP binding protein overexpressed in skeletal muscle
GREB1 growth regulation by estrogen in breast cancer 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
IER2 immediate early response 2
IER3 immediate early response 3
IER5 immediate early response 5
IFI27 interferon, alpha-inducible protein 27
KLK6 kallikrein-related peptidase 6
LCN2 lipocalin 2
LTF lactotransferrin
LXN latexin
LYZ lysozyme
MIR22HG MIR22 host gene
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIL3 nuclear factor, interleukin 3 regulated
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRIP1 nuclear receptor interacting protein 1
NUP98 nucleoporin 98kDa
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHLDA2 pleckstrin homology-like domain, family A, member 2
POLR1C polymerase (RNA) I polypeptide C, 30kDa
SCAF8 SR-related CTD-associated factor 8
SDC4 syndecan 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFF1 trefoil factor 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM255A transmembrane protein 255A
TRPS1 trichorhinophalangeal syndrome I
WTAP Wilms tumor 1 associated protein
XBP1 X-box binding protein 1
ZFP36 ZFP36 ring finger protein
ZFP36L2 ZFP36 ring finger protein-like 2