BRD-K79018442_KIN001-260;_HEPG2_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K79018442_KIN001-260;_HEPG2_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM9 ADAM metallopeptidase domain 9
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA1 annexin A1
APOD apolipoprotein D
ARHGAP29 Rho GTPase activating protein 29
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BIK BCL2-interacting killer (apoptosis-inducing)
C10ORF10 chromosome 10 open reading frame 10
CALML5 calmodulin-like 5
CRIP1 cysteine-rich protein 1 (intestinal)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTGF connective tissue growth factor
CTSD cathepsin D
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP6 dual specificity phosphatase 6
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
F13A1 coagulation factor XIII, A1 polypeptide
GLRX glutaredoxin (thioltransferase)
ITGA6 integrin, alpha 6
MMP7 matrix metallopeptidase 7
MVP major vault protein
MYOF myoferlin
NCKAP1 NCK-associated protein 1
PDLIM5 PDZ and LIM domain 5
PDZK1IP1 PDZK1 interacting protein 1
PERP PERP, TP53 apoptosis effector
PSCA prostate stem cell antigen
RAP1GAP RAP1 GTPase activating protein
SIRT3 sirtuin 3
SQRDL sulfide quinone reductase-like (yeast)
STXBP2 syntaxin binding protein 2
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TM4SF1 transmembrane 4 L six family member 1
VNN1 vanin 1

decreased expression

Symbol Name
ADAM19 ADAM metallopeptidase domain 19
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
BEX1 brain expressed, X-linked 1
CA1 carbonic anhydrase I
CADM1 cell adhesion molecule 1
CDC20 cell division cycle 20
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
COX17 COX17 cytochrome c oxidase copper chaperone
CSTA cystatin A (stefin A)
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
EXOSC4 exosome component 4
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
GRWD1 glutamate-rich WD repeat containing 1
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LOXL1 lysyl oxidase-like 1
MAL mal, T-cell differentiation protein
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR1H2 nuclear receptor subfamily 1, group H, member 2
NREP neuronal regeneration related protein
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
ODC1 ornithine decarboxylase 1
P3H2 prolyl 3-hydroxylase 2
PRC1 protein regulator of cytokinesis 1
PRDX2 peroxiredoxin 2
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RPL27A ribosomal protein L27a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
TFF3 trefoil factor 3 (intestinal)
VCAM1 vascular cell adhesion molecule 1