BRD-K78930611_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

99 genes differentially expressed following the BRD-K78930611_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCY1 adenylate cyclase 1 (brain)
ANKRD10 ankyrin repeat domain 10
ARMCX3 armadillo repeat containing, X-linked 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CA2 carbonic anhydrase II
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CRIP1 cysteine-rich protein 1 (intestinal)
EDN1 endothelin 1
EIF5A eukaryotic translation initiation factor 5A
ELANE elastase, neutrophil expressed
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FABP4 fatty acid binding protein 4, adipocyte
FAM46C family with sequence similarity 46, member C
FHL1 four and a half LIM domains 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FRZB frizzled-related protein
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GREM1 gremlin 1, DAN family BMP antagonist
H2BFS H2B histone family, member S (pseudogene)
HBB hemoglobin, beta
HBD hemoglobin, delta
HBE1 hemoglobin, epsilon 1
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
HIST1H2BK histone cluster 1, H2bk
HIST2H2BE histone cluster 2, H2be
HSPA1A heat shock 70kDa protein 1A
JUN jun proto-oncogene
LOC100505650 uncharacterized LOC100505650
LPPR4 lipid phosphate phosphatase-related protein type 4
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP7 microtubule-associated protein 7
MT1M metallothionein 1M
MXRA7 matrix-remodelling associated 7
NPY neuropeptide Y
NPY1R neuropeptide Y receptor Y1
NRGN neurogranin (protein kinase C substrate, RC3)
OPHN1 oligophrenin 1
ORC1 origin recognition complex, subunit 1
PON3 paraoxonase 3
PRUNE2 prune homolog 2 (Drosophila)
QPCT glutaminyl-peptide cyclotransferase
RAB3B RAB3B, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
SCG2 secretogranin II
SESN1 sestrin 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SPON1 spondin 1, extracellular matrix protein
SST somatostatin
STX1A syntaxin 1A (brain)
TGFBR3 transforming growth factor, beta receptor III
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TSPYL5 TSPY-like 5

decreased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
AKAP13 A kinase (PRKA) anchor protein 13
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
BASP1 brain abundant, membrane attached signal protein 1
BST2 bone marrow stromal cell antigen 2
CA12 carbonic anhydrase XII
CD14 CD14 molecule
CDA cytidine deaminase
CDKN2A cyclin-dependent kinase inhibitor 2A
CPNE3 copine III
CRYAB crystallin, alpha B
CYB5A cytochrome b5 type A (microsomal)
EHBP1 EH domain binding protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
GOLM1 golgi membrane protein 1
IFI27 interferon, alpha-inducible protein 27
IFI44L interferon-induced protein 44-like
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
INHBB inhibin, beta B
KCTD12 potassium channel tetramerization domain containing 12
KIAA1033 KIAA1033
LPL lipoprotein lipase
MBP myelin basic protein
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFIB nuclear factor I/B
PCM1 pericentriolar material 1
PDZD2 PDZ domain containing 2
PI3 peptidase inhibitor 3, skin-derived
PPA1 pyrophosphatase (inorganic) 1
PRKCD protein kinase C, delta
RBM47 RNA binding motif protein 47
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TJP2 tight junction protein 2
TKT transketolase
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TREM1 triggering receptor expressed on myeloid cells 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
WSB1 WD repeat and SOCS box containing 1
ZFAND5 zinc finger, AN1-type domain 5