BRD-K78930611_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-K78930611_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C3 aldo-keto reductase family 1, member C3
ALB albumin
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANKRD10 ankyrin repeat domain 10
ANKRD36B ankyrin repeat domain 36B
ARID4B AT rich interactive domain 4B (RBP1-like)
ASS1 argininosuccinate synthase 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL6 B-cell CLL/lymphoma 6
C1S complement component 1, s subcomponent
CCNG2 cyclin G2
CRIP1 cysteine-rich protein 1 (intestinal)
CST3 cystatin C
CTSB cathepsin B
DDIT4 DNA-damage-inducible transcript 4
GNAS GNAS complex locus
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRN granulin
HBB hemoglobin, beta
HMOX1 heme oxygenase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IL17RB interleukin 17 receptor B
LINC00341 long intergenic non-protein coding RNA 341
MAN1A1 mannosidase, alpha, class 1A, member 1
METTL7A methyltransferase like 7A
MFAP5 microfibrillar associated protein 5
MXRA5 matrix-remodelling associated 5
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NELL2 NEL-like 2 (chicken)
NPY1R neuropeptide Y receptor Y1
NUPR1 nuclear protein, transcriptional regulator, 1
PCDH9 protocadherin 9
PCOLCE2 procollagen C-endopeptidase enhancer 2
PCP4 Purkinje cell protein 4
PCSK1 proprotein convertase subtilisin/kexin type 1
PERP PERP, TP53 apoptosis effector
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PROM1 prominin 1
QPCT glutaminyl-peptide cyclotransferase
RAD9A RAD9 homolog A (S. pombe)
RAP1GAP2 RAP1 GTPase activating protein 2
RFX5 regulatory factor X, 5 (influences HLA class II expression)
S100P S100 calcium binding protein P
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SORBS1 sorbin and SH3 domain containing 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TGFBR3 transforming growth factor, beta receptor III
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TOB1 transducer of ERBB2, 1
TRPS1 trichorhinophalangeal syndrome I
TSPAN13 tetraspanin 13
TUBB2B tubulin, beta 2B class IIb
XYLT1 xylosyltransferase I
ZNF131 zinc finger protein 131

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ANXA3 annexin A3
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BIRC3 baculoviral IAP repeat containing 3
BST2 bone marrow stromal cell antigen 2
CAV2 caveolin 2
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CNN3 calponin 3, acidic
CPM carboxypeptidase M
CYB5A cytochrome b5 type A (microsomal)
DUSP5 dual specificity phosphatase 5
EDN1 endothelin 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFNB2 ephrin-B2
EGFR epidermal growth factor receptor
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GRAMD3 GRAM domain containing 3
IGHM immunoglobulin heavy constant mu
IGKV4-1 immunoglobulin kappa variable 4-1
JCHAIN joining chain of multimeric IgA and IgM
KIAA1033 KIAA1033
LGALS2 lectin, galactoside-binding, soluble, 2
LITAF lipopolysaccharide-induced TNF factor
LPAR1 lysophosphatidic acid receptor 1
MBP myelin basic protein
MMP19 matrix metallopeptidase 19
OPN3 opsin 3
PDGFA platelet-derived growth factor alpha polypeptide
PDLIM5 PDZ and LIM domain 5
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RFTN1 raftlin, lipid raft linker 1
RGS1 regulator of G-protein signaling 1
SDC4 syndecan 4
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SRGN serglycin
STAMBP STAM binding protein
THBS1 thrombospondin 1