BRD-K78930611_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

59 genes differentially expressed following the BRD-K78930611_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
AQP9 aquaporin 9
CLC Charcot-Leyden crystal galectin
CRIP2 cysteine-rich protein 2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GAL galanin/GMAP prepropeptide
GCH1 GTP cyclohydrolase 1
H2BFS H2B histone family, member S (pseudogene)
HBB hemoglobin, beta
HHEX hematopoietically expressed homeobox
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
HIST1H2BK histone cluster 1, H2bk
ITM2A integral membrane protein 2A
KDM5D lysine (K)-specific demethylase 5D
LITAF lipopolysaccharide-induced TNF factor
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MMP9 matrix metallopeptidase 9
MUC5B mucin 5B, oligomeric mucus/gel-forming
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RGS2 regulator of G-protein signaling 2
RPL22 ribosomal protein L22
RPS4Y1 ribosomal protein S4, Y-linked 1
S100P S100 calcium binding protein P
SCG2 secretogranin II
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AXL AXL receptor tyrosine kinase
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
CCND1 cyclin D1
CHD7 chromodomain helicase DNA binding protein 7
CTGF connective tissue growth factor
DHRS2 dehydrogenase/reductase (SDR family) member 2
DKK1 dickkopf WNT signaling pathway inhibitor 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FPGS folylpolyglutamate synthase
HBEGF heparin-binding EGF-like growth factor
IGFBP3 insulin-like growth factor binding protein 3
KIAA0020 KIAA0020
LCN2 lipocalin 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRSS23 protease, serine, 23
PSIP1 PC4 and SFRS1 interacting protein 1
RND3 Rho family GTPase 3
RPS11 ribosomal protein S11
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SMAD3 SMAD family member 3
SRPX sushi-repeat containing protein, X-linked
TCTA T-cell leukemia translocation altered
THBS1 thrombospondin 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
ZNF451 zinc finger protein 451