BRD-K78716413_Compound 10_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-K78716413_Compound 10_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK4 adenylate kinase 4
ANXA4 annexin A4
CBS cystathionine-beta-synthase
CFB complement factor B
CORO1A coronin, actin binding protein, 1A
DDIT4 DNA-damage-inducible transcript 4
FOXG1 forkhead box G1
GRN granulin
INSIG1 insulin induced gene 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KDM3A lysine (K)-specific demethylase 3A
LMO3 LIM domain only 3 (rhombotin-like 2)
LYN LYN proto-oncogene, Src family tyrosine kinase
MLF1 myeloid leukemia factor 1
NAMPT nicotinamide phosphoribosyltransferase
NMU neuromedin U
PNMA2 paraneoplastic Ma antigen 2
PSPH phosphoserine phosphatase
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLC22A18 solute carrier family 22, member 18
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b

decreased expression

Symbol Name
ACP5 acid phosphatase 5, tartrate resistant
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ATF5 activating transcription factor 5
COL15A1 collagen, type XV, alpha 1
DCN decorin
DPT dermatopontin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBLN1 fibulin 1
IGFBP7 insulin-like growth factor binding protein 7
KEAP1 kelch-like ECH-associated protein 1
MMP12 matrix metallopeptidase 12
NFIB nuclear factor I/B
NR2F2 nuclear receptor subfamily 2, group F, member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGK1 serum/glucocorticoid regulated kinase 1
TGFBR3 transforming growth factor, beta receptor III
TMEM5 transmembrane protein 5
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)