BRD-K78549347_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

51 genes differentially expressed following the BRD-K78549347_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AP2M1 adaptor-related protein complex 2, mu 1 subunit
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DUSP5 dual specificity phosphatase 5
F13A1 coagulation factor XIII, A1 polypeptide
G6PD glucose-6-phosphate dehydrogenase
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GSTA1 glutathione S-transferase alpha 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMOX1 heme oxygenase 1
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT6A keratin 6A, type II
KYNU kynureninase
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NAMPT nicotinamide phosphoribosyltransferase
NEBL nebulette
NQO1 NAD(P)H dehydrogenase, quinone 1
PALLD palladin, cytoskeletal associated protein
PGD phosphogluconate dehydrogenase
PPAP2C phosphatidic acid phosphatase type 2C
PRDX2 peroxiredoxin 2
RAP1GAP RAP1 GTPase activating protein
SQSTM1 sequestosome 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TRIM16 tripartite motif containing 16
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
CA2 carbonic anhydrase II
ERBB4 erb-b2 receptor tyrosine kinase 4
FAM46A family with sequence similarity 46, member A
KRT23 keratin 23, type I
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYZ lysozyme
NR4A2 nuclear receptor subfamily 4, group A, member 2
TOB1 transducer of ERBB2, 1
TSPAN4 tetraspanin 4
ZBTB18 zinc finger and BTB domain containing 18