BRD-K78431006_crizotinib_MDAMB231_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

22 genes differentially expressed following the BRD-K78431006_crizotinib_MDAMB231_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CLU clusterin
GCLC glutamate-cysteine ligase, catalytic subunit
LEF1 lymphoid enhancer-binding factor 1
MAP7 microtubule-associated protein 7
MMP7 matrix metallopeptidase 7
NUPR1 nuclear protein, transcriptional regulator, 1
ORAI3 ORAI calcium release-activated calcium modulator 3
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PEG10 paternally expressed 10
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBKS ribokinase
RGS2 regulator of G-protein signaling 2
SAT1 spermidine/spermine N1-acetyltransferase 1
TRPS1 trichorhinophalangeal syndrome I
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CRISP3 cysteine-rich secretory protein 3
DHRS2 dehydrogenase/reductase (SDR family) member 2
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
KIF14 kinesin family member 14
TPR translocated promoter region, nuclear basket protein