BRD-K78373679_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K78373679_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALB albumin
ANKRD10 ankyrin repeat domain 10
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BCL6 B-cell CLL/lymphoma 6
CD44 CD44 molecule (Indian blood group)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN1 chimerin 1
COL11A1 collagen, type XI, alpha 1
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
ENO2 enolase 2 (gamma, neuronal)
FRZB frizzled-related protein
GCH1 GTP cyclohydrolase 1
GREM1 gremlin 1, DAN family BMP antagonist
H2BFS H2B histone family, member S (pseudogene)
HBB hemoglobin, beta
HIST1H1C histone cluster 1, H1c
HIST1H2BD histone cluster 1, H2bd
HOPX HOP homeobox
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGFBP5 insulin-like growth factor binding protein 5
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MT1E metallothionein 1E
MT1F metallothionein 1F
NOX4 NADPH oxidase 4
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
POSTN periostin, osteoblast specific factor
PRNP prion protein
PTGER4 prostaglandin E receptor 4 (subtype EP4)
SCG2 secretogranin II
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SULF1 sulfatase 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TXNL4B thioredoxin-like 4B
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ACP5 acid phosphatase 5, tartrate resistant
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AQP3 aquaporin 3 (Gill blood group)
BASP1 brain abundant, membrane attached signal protein 1
CCND2 cyclin D2
CHD7 chromodomain helicase DNA binding protein 7
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
COL9A3 collagen, type IX, alpha 3
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL12 chemokine (C-X-C motif) ligand 12
DACH1 dachshund family transcription factor 1
GRB14 growth factor receptor-bound protein 14
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
INTS3 integrator complex subunit 3
KIF14 kinesin family member 14
KLF4 Kruppel-like factor 4 (gut)
LBR lamin B receptor
ODC1 ornithine decarboxylase 1
PCM1 pericentriolar material 1
PLA1A phospholipase A1 member A
PSIP1 PC4 and SFRS1 interacting protein 1
QKI QKI, KH domain containing, RNA binding
RNF167 ring finger protein 167
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAMBP STAM binding protein
UBAP2 ubiquitin associated protein 2
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
YBX3 Y box binding protein 3