BRD-K78126613_MENADIONE_A549_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K78126613_MENADIONE_A549_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
AMIGO2 adhesion molecule with Ig-like domain 2
AREG amphiregulin
BBX bobby sox homolog (Drosophila)
C6ORF48 chromosome 6 open reading frame 48
CA12 carbonic anhydrase XII
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COMP cartilage oligomeric matrix protein
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FAS Fas cell surface death receptor
GLUL glutamate-ammonia ligase
HBB hemoglobin, beta
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INPP1 inositol polyphosphate-1-phosphatase
PLA2G16 phospholipase A2, group XVI
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RBP4 retinol binding protein 4, plasma
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SAT1 spermidine/spermine N1-acetyltransferase 1
TFF1 trefoil factor 1
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein
XBP1 X-box binding protein 1

decreased expression

Symbol Name
AURKA aurora kinase A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EDNRB endothelin receptor type B
FABP7 fatty acid binding protein 7, brain
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL7R interleukin 7 receptor
ITGA6 integrin, alpha 6
LEF1 lymphoid enhancer-binding factor 1
LOC100505650 uncharacterized LOC100505650
LYST lysosomal trafficking regulator
P3H2 prolyl 3-hydroxylase 2
SVIL supervillin
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
WT1 Wilms tumor 1