BRD-K78126613_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

83 genes differentially expressed following the BRD-K78126613_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADORA2B adenosine A2b receptor
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
BTG2 BTG family, member 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CAST calpastatin
CD40 CD40 molecule, TNF receptor superfamily member 5
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
EXT1 exostosin glycosyltransferase 1
FGG fibrinogen gamma chain
FN1 fibronectin 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GAREM GRB2 associated, regulator of MAPK1
GPRC5A G protein-coupled receptor, class C, group 5, member A
HMOX1 heme oxygenase 1
HOPX HOP homeobox
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IPO13 importin 13
KCTD12 potassium channel tetramerization domain containing 12
KRT6B keratin 6B, type II
KYNU kynureninase
LIMCH1 LIM and calponin homology domains 1
MMP7 matrix metallopeptidase 7
OBSL1 obscurin-like 1
PAPD7 PAP associated domain containing 7
RAP1GAP RAP1 GTPase activating protein
RND3 Rho family GTPase 3
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
S100A8 S100 calcium binding protein A8
SCCPDH saccharopine dehydrogenase (putative)
SDC1 syndecan 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SRGN serglycin
TES testin LIM domain protein
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIM16 tripartite motif containing 16
TSKU tsukushi, small leucine rich proteoglycan
TSPAN8 tetraspanin 8
TXNRD1 thioredoxin reductase 1
VAT1 vesicle amine transport 1
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AGR2 anterior gradient 2
AKAP7 A kinase (PRKA) anchor protein 7
BCL2 B-cell CLL/lymphoma 2
CADM1 cell adhesion molecule 1
CKS2 CDC28 protein kinase regulatory subunit 2
EPCAM epithelial cell adhesion molecule
ESR1 estrogen receptor 1
EVL Enah/Vasp-like
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
IGFBP5 insulin-like growth factor binding protein 5
IL6ST interleukin 6 signal transducer
LOX lysyl oxidase
MUC1 mucin 1, cell surface associated
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NPY neuropeptide Y
NR1D2 nuclear receptor subfamily 1, group D, member 2
PDZK1 PDZ domain containing 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PTN pleiotrophin
PTP4A2 protein tyrosine phosphatase type IVA, member 2
RCAN1 regulator of calcineurin 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SPDEF SAM pointed domain containing ETS transcription factor
SRPX sushi-repeat containing protein, X-linked
SRSF6 serine/arginine-rich splicing factor 6
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TMEM47 transmembrane protein 47
TNC tenascin C
TTC3 tetratricopeptide repeat domain 3