BRD-K77987382_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K77987382_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL3 acyl-CoA synthetase long-chain family member 3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AGR2 anterior gradient 2
ANKRD10 ankyrin repeat domain 10
ANXA1 annexin A1
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ASPN asporin
ATF3 activating transcription factor 3
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
C10ORF10 chromosome 10 open reading frame 10
CAV1 caveolin 1, caveolae protein, 22kDa
CD44 CD44 molecule (Indian blood group)
CD58 CD58 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CSNK1E casein kinase 1, epsilon
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
DSTN destrin (actin depolymerizing factor)
DUSP4 dual specificity phosphatase 4
FABP4 fatty acid binding protein 4, adipocyte
FADS1 fatty acid desaturase 1
FAM129A family with sequence similarity 129, member A
FBLN1 fibulin 1
FHL1 four and a half LIM domains 1
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
HBEGF heparin-binding EGF-like growth factor
IER3 immediate early response 3
ITGA6 integrin, alpha 6
ITM2A integral membrane protein 2A
JUN jun proto-oncogene
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDSR 3-ketodihydrosphingosine reductase
LDLR low density lipoprotein receptor
MACF1 microtubule-actin crosslinking factor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBNL2 muscleblind-like splicing regulator 2
MCOLN1 mucolipin 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRN1 neuritin 1
PLAT plasminogen activator, tissue
PLTP phospholipid transfer protein
POSTN periostin, osteoblast specific factor
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRNP prion protein
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RRBP1 ribosome binding protein 1
SDC4 syndecan 4
SRSF6 serine/arginine-rich splicing factor 6
STC2 stanniocalcin 2
TIAM1 T-cell lymphoma invasion and metastasis 1
TLR4 toll-like receptor 4
TMX4 thioredoxin-related transmembrane protein 4
TRIB2 tribbles pseudokinase 2
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
BLNK B-cell linker
BPHL biphenyl hydrolase-like (serine hydrolase)
CA12 carbonic anhydrase XII
CD24 CD24 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CLDN3 claudin 3
CRABP2 cellular retinoic acid binding protein 2
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DLK1 delta-like 1 homolog (Drosophila)
DSC2 desmocollin 2
HOXC6 homeobox C6
IFITM1 interferon induced transmembrane protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KIAA0101 KIAA0101
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT23 keratin 23, type I
MAP7 microtubule-associated protein 7
MME membrane metallo-endopeptidase
MMP7 matrix metallopeptidase 7
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
PCOLCE procollagen C-endopeptidase enhancer
PRKCI protein kinase C, iota
RTN2 reticulon 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TARP TCR gamma alternate reading frame protein
TUSC3 tumor suppressor candidate 3
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon