BRD-K77908580_entinostat_HEPG2_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

144 genes differentially expressed following the BRD-K77908580_entinostat_HEPG2_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACBD3 acyl-CoA binding domain containing 3
ACTG2 actin, gamma 2, smooth muscle, enteric
ALDOC aldolase C, fructose-bisphosphate
ANXA2P2 annexin A2 pseudogene 2
ASMTL acetylserotonin O-methyltransferase-like
BAMBI BMP and activin membrane-bound inhibitor
BASP1 brain abundant, membrane attached signal protein 1
CALU calumenin
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CD24 CD24 molecule
CD44 CD44 molecule (Indian blood group)
CD81 CD81 molecule
CDC42 cell division cycle 42
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL6A3 collagen, type VI, alpha 3
CORO1A coronin, actin binding protein, 1A
COTL1 coactosin-like F-actin binding protein 1
CREM cAMP responsive element modulator
CTBP2 C-terminal binding protein 2
CTSB cathepsin B
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL5 chemokine (C-X-C motif) ligand 5
CYB561 cytochrome b561
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DUSP6 dual specificity phosphatase 6
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBLN1 fibulin 1
FOXO4 forkhead box O4
G0S2 G0/G1 switch 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GOLM1 golgi membrane protein 1
HLA-E major histocompatibility complex, class I, E
HMG20B high mobility group 20B
HOXA10 homeobox A10
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IGL immunoglobulin lambda locus
IRS1 insulin receptor substrate 1
JARID2 jumonji, AT rich interactive domain 2
LGALS1 lectin, galactoside-binding, soluble, 1
LGMN legumain
LITAF lipopolysaccharide-induced TNF factor
LRP10 low density lipoprotein receptor-related protein 10
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LUM lumican
MAPT microtubule-associated protein tau
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMP7 matrix metallopeptidase 7
MSN moesin
MTSS1 metastasis suppressor 1
MXI1 MAX interactor 1, dimerization protein
NLRP2 NLR family, pyrin domain containing 2
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OLFM1 olfactomedin 1
OLFM4 olfactomedin 4
OLFML3 olfactomedin-like 3
OPHN1 oligophrenin 1
PALLD palladin, cytoskeletal associated protein
PDLIM1 PDZ and LIM domain 1
POSTN periostin, osteoblast specific factor
PSPH phosphoserine phosphatase
PTN pleiotrophin
RAB31 RAB31, member RAS oncogene family
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RCAN1 regulator of calcineurin 1
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
RPS5 ribosomal protein S5
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
S100A6 S100 calcium binding protein A6
SCD5 stearoyl-CoA desaturase 5
SCPEP1 serine carboxypeptidase 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SFN stratifin
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SOX9 SRY (sex determining region Y)-box 9
STOM stomatin
STXBP1 syntaxin binding protein 1
SULF1 sulfatase 1
TIMP1 TIMP metallopeptidase inhibitor 1
TNC tenascin C
TPD52 tumor protein D52
TRAPPC6A trafficking protein particle complex 6A
TUBB2B tubulin, beta 2B class IIb
TXNRD1 thioredoxin reductase 1
WDTC1 WD and tetratricopeptide repeats 1
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANPEP alanyl (membrane) aminopeptidase
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CCNA2 cyclin A2
CDC25A cell division cycle 25A
CFB complement factor B
CLU clusterin
DCK deoxycytidine kinase
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLC1 DLC1 Rho GTPase activating protein
DLK1 delta-like 1 homolog (Drosophila)
EIF5 eukaryotic translation initiation factor 5
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FGFR3 fibroblast growth factor receptor 3
GTPBP8 GTP-binding protein 8 (putative)
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
KIAA0368 KIAA0368
KRT13 keratin 13, type I
LHX2 LIM homeobox 2
LOC100505650 uncharacterized LOC100505650
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MSLN mesothelin
MUC16 mucin 16, cell surface associated
PLAGL1 pleiomorphic adenoma gene-like 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPIC peptidylprolyl isomerase C (cyclophilin C)
PPIF peptidylprolyl isomerase F
PTX3 pentraxin 3, long
PXMP2 peroxisomal membrane protein 2, 22kDa
SEPP1 selenoprotein P, plasma, 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SPRR1A small proline-rich protein 1A
SPRR3 small proline-rich protein 3
TACC3 transforming, acidic coiled-coil containing protein 3
TP53 tumor protein p53
TYRP1 tyrosinase-related protein 1
UBE2C ubiquitin-conjugating enzyme E2C
VCAN versican
ZNF185 zinc finger protein 185 (LIM domain)