BRD-K77908580_entinostat_A549_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K77908580_entinostat_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ADGRG1 adhesion G protein-coupled receptor G1
C6ORF62 chromosome 6 open reading frame 62
CD44 CD44 molecule (Indian blood group)
CEMIP cell migration inducing protein, hyaluronan binding
CLEC2B C-type lectin domain family 2, member B
CRIP1 cysteine-rich protein 1 (intestinal)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
EIF4B eukaryotic translation initiation factor 4B
ENO2 enolase 2 (gamma, neuronal)
FADS1 fatty acid desaturase 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IER3 immediate early response 3
INHBA inhibin, beta A
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LMCD1 LIM and cysteine-rich domains 1
MLF1 myeloid leukemia factor 1
MMD monocyte to macrophage differentiation-associated
MT1X metallothionein 1X
MYO1B myosin IB
NR4A1 nuclear receptor subfamily 4, group A, member 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAM peptidylglycine alpha-amidating monooxygenase
PLIN2 perilipin 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RCAN1 regulator of calcineurin 1
SOX4 SRY (sex determining region Y)-box 4
SYNGR3 synaptogyrin 3

decreased expression

Symbol Name
ATF5 activating transcription factor 5
CFLAR CASP8 and FADD-like apoptosis regulator
COBLL1 cordon-bleu WH2 repeat protein-like 1
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CXCL14 chemokine (C-X-C motif) ligand 14
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EFS embryonal Fyn-associated substrate
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
JADE2 jade family PHD finger 2
LTF lactotransferrin
PITX1 paired-like homeodomain 1
PTPRC protein tyrosine phosphatase, receptor type, C
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SETBP1 SET binding protein 1
TP53 tumor protein p53
ZDHHC6 zinc finger, DHHC-type containing 6