BRD-K77908580_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K77908580_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADD3 adducin 3 (gamma)
ADGRG1 adhesion G protein-coupled receptor G1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKR1C3 aldo-keto reductase family 1, member C3
ANXA4 annexin A4
ARHGAP29 Rho GTPase activating protein 29
BLVRA biliverdin reductase A
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
EFNB2 ephrin-B2
F12 coagulation factor XII (Hageman factor)
FHL1 four and a half LIM domains 1
GDF15 growth differentiation factor 15
GPX1 glutathione peroxidase 1
IER3 immediate early response 3
KRT18 keratin 18, type I
KRT7 keratin 7, type II
LTA4H leukotriene A4 hydrolase
MALL mal, T-cell differentiation protein-like
MFAP5 microfibrillar associated protein 5
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFIB nuclear factor I/B
NMU neuromedin U
NQO1 NAD(P)H dehydrogenase, quinone 1
NRIP1 nuclear receptor interacting protein 1
PDGFA platelet-derived growth factor alpha polypeptide
PFKM phosphofructokinase, muscle
PLK2 polo-like kinase 2
PRR7 proline rich 7 (synaptic)
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
SLC22A18 solute carrier family 22, member 18
SMAD3 SMAD family member 3
SRPX sushi-repeat containing protein, X-linked
STXBP1 syntaxin binding protein 1
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TARBP1 TAR (HIV-1) RNA binding protein 1
TBPL1 TBP-like 1
TM4SF1 transmembrane 4 L six family member 1
TSPAN4 tetraspanin 4
TSPAN8 tetraspanin 8
TUBA1A tubulin, alpha 1a

decreased expression

Symbol Name
COL11A1 collagen, type XI, alpha 1
COL6A1 collagen, type VI, alpha 1
CXCL13 chemokine (C-X-C motif) ligand 13
DHRS2 dehydrogenase/reductase (SDR family) member 2
FOSL1 FOS-like antigen 1
GABPB1 GA binding protein transcription factor, beta subunit 1
IGHMBP2 immunoglobulin mu binding protein 2
JMJD6 jumonji domain containing 6
KLHL21 kelch-like family member 21
KYNU kynureninase
QKI QKI, KH domain containing, RNA binding
RGS1 regulator of G-protein signaling 1
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
S100A7 S100 calcium binding protein A7
SRGN serglycin
STEAP3 STEAP family member 3, metalloreductase
TDO2 tryptophan 2,3-dioxygenase