BRD-K77830450_forskolin_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

97 genes differentially expressed following the BRD-K77830450_forskolin_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ANO1 anoctamin 1, calcium activated chloride channel
AQP1 aquaporin 1 (Colton blood group)
ARG2 arginase 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BLNK B-cell linker
CD200 CD200 molecule
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CKB creatine kinase, brain
COCH cochlin
COL2A1 collagen, type II, alpha 1
CRABP1 cellular retinoic acid binding protein 1
CREM cAMP responsive element modulator
CRISP3 cysteine-rich secretory protein 3
CXCL13 chemokine (C-X-C motif) ligand 13
DLK1 delta-like 1 homolog (Drosophila)
DUSP4 dual specificity phosphatase 4
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EPAS1 endothelial PAS domain protein 1
FGFR2 fibroblast growth factor receptor 2
FOLR1 folate receptor 1 (adult)
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GAL galanin/GMAP prepropeptide
GSTA1 glutathione S-transferase alpha 1
H1F0 H1 histone family, member 0
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IGF1R insulin-like growth factor 1 receptor
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP5 insulin-like growth factor binding protein 5
ISOC1 isochorismatase domain containing 1
ISYNA1 inositol-3-phosphate synthase 1
KRT23 keratin 23, type I
LPAR2 lysophosphatidic acid receptor 2
LPAR6 lysophosphatidic acid receptor 6
LYZ lysozyme
MGP matrix Gla protein
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
NBEA neurobeachin
NPTX2 neuronal pentraxin II
PCP4 Purkinje cell protein 4
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM5 PDZ and LIM domain 5
PRAME preferentially expressed antigen in melanoma
PROM1 prominin 1
PTK2 protein tyrosine kinase 2
RGCC regulator of cell cycle
RGS2 regulator of G-protein signaling 2
S100A8 S100 calcium binding protein A8
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SFRP1 secreted frizzled-related protein 1
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TBL1X transducin (beta)-like 1X-linked
TMSB15A thymosin beta 15a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRPS1 trichorhinophalangeal syndrome I

decreased expression

Symbol Name
ADM adrenomedullin
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
C6ORF62 chromosome 6 open reading frame 62
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CELF2 CUGBP, Elav-like family member 2
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLC1 DLC1 Rho GTPase activating protein
FADS1 fatty acid desaturase 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GMFB glia maturation factor, beta
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ITM2A integral membrane protein 2A
LDLR low density lipoprotein receptor
MAPK6 mitogen-activated protein kinase 6
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NME1 NME/NM23 nucleoside diphosphate kinase 1
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PLAU plasminogen activator, urokinase
PTX3 pentraxin 3, long
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG5 secretogranin V
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SPAG4 sperm associated antigen 4
THY1 Thy-1 cell surface antigen
TNC tenascin C
TNIP1 TNFAIP3 interacting protein 1