BRD-K77830450_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

96 genes differentially expressed following the BRD-K77830450_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMDHD2 amidohydrolase domain containing 2
AOX1 aldehyde oxidase 1
AREG amphiregulin
ASPH aspartate beta-hydroxylase
BASP1 brain abundant, membrane attached signal protein 1
BCL2 B-cell CLL/lymphoma 2
BEX1 brain expressed, X-linked 1
CA2 carbonic anhydrase II
CAP2 CAP, adenylate cyclase-associated protein, 2 (yeast)
CAPG capping protein (actin filament), gelsolin-like
CD24 CD24 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHGB chromogranin B
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
CRABP1 cellular retinoic acid binding protein 1
CRABP2 cellular retinoic acid binding protein 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DEPTOR DEP domain containing MTOR-interacting protein
DUSP4 dual specificity phosphatase 4
ECHDC3 enoyl CoA hydratase domain containing 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
G0S2 G0/G1 switch 2
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GLDC glycine dehydrogenase (decarboxylating)
GLRX glutaredoxin (thioltransferase)
GPD1L glycerol-3-phosphate dehydrogenase 1-like
GPX3 glutathione peroxidase 3
GREM1 gremlin 1, DAN family BMP antagonist
HOPX HOP homeobox
HOXA5 homeobox A5
IER3 immediate early response 3
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
IGFBP3 insulin-like growth factor binding protein 3
ITGB5 integrin, beta 5
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LPGAT1 lysophosphatidylglycerol acyltransferase 1
LXN latexin
MCAM melanoma cell adhesion molecule
MSMO1 methylsterol monooxygenase 1
MXRA7 matrix-remodelling associated 7
MYC v-myc avian myelocytomatosis viral oncogene homolog
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NPTX2 neuronal pentraxin II
NSG1 neuron specific gene family member 1
OLFM4 olfactomedin 4
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCP4 Purkinje cell protein 4
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RAP1GAP RAP1 GTPase activating protein
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SH3BP5 SH3-domain binding protein 5 (BTK-associated)
SKAP2 src kinase associated phosphoprotein 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFF3 trefoil factor 3 (intestinal)
TIMP1 TIMP metallopeptidase inhibitor 1
TMEM2 transmembrane protein 2
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VCAN versican
VIM vimentin

decreased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
C1ORF116 chromosome 1 open reading frame 116
CAST calpastatin
CCND2 cyclin D2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL7A1 collagen, type VII, alpha 1
CXCL11 chemokine (C-X-C motif) ligand 11
DKK1 dickkopf WNT signaling pathway inhibitor 1
DMD dystrophin
DPYD dihydropyrimidine dehydrogenase
ECM1 extracellular matrix protein 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GBP1 guanylate binding protein 1, interferon-inducible
HSPA1A heat shock 70kDa protein 1A
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
MAGEA6 melanoma antigen family A6
MYBPC1 myosin binding protein C, slow type
NRCAM neuronal cell adhesion molecule
NXN nucleoredoxin
SCEL sciellin
SHB Src homology 2 domain containing adaptor protein B
SLCO1B3 solute carrier organic anion transporter family, member 1B3
TDO2 tryptophan 2,3-dioxygenase
TMPRSS2 transmembrane protease, serine 2