BRD-K77830450_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

40 genes differentially expressed following the BRD-K77830450_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AGR2 anterior gradient 2
CLDND1 claudin domain containing 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
EIF5A eukaryotic translation initiation factor 5A
FGFR4 fibroblast growth factor receptor 4
FOS FBJ murine osteosarcoma viral oncogene homolog
IL6ST interleukin 6 signal transducer
KLHL2 kelch-like family member 2
KRT18 keratin 18, type I
LGMN legumain
NET1 neuroepithelial cell transforming 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERTAD2 SERTA domain containing 2
SGK1 serum/glucocorticoid regulated kinase 1
SPDEF SAM pointed domain containing ETS transcription factor
STXBP1 syntaxin binding protein 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)

decreased expression

Symbol Name
ARHGAP29 Rho GTPase activating protein 29
ARID5B AT rich interactive domain 5B (MRF1-like)
GADD45A growth arrest and DNA-damage-inducible, alpha
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPB1 heat shock 27kDa protein 1
IGHM immunoglobulin heavy constant mu
KLK5 kallikrein-related peptidase 5
PTP4A3 protein tyrosine phosphatase type IVA, member 3
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SOX4 SRY (sex determining region Y)-box 4
TRIB3 tribbles pseudokinase 3
VCAM1 vascular cell adhesion molecule 1
ZNF395 zinc finger protein 395