BRD-K77554836_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K77554836_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
AREG amphiregulin
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
C10ORF10 chromosome 10 open reading frame 10
CD9 CD9 molecule
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
DDIT4 DNA-damage-inducible transcript 4
FHL1 four and a half LIM domains 1
FILIP1L filamin A interacting protein 1-like
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HOPX HOP homeobox
JCHAIN joining chain of multimeric IgA and IgM
KANK1 KN motif and ankyrin repeat domains 1
MN1 meningioma (disrupted in balanced translocation) 1
MYH11 myosin, heavy chain 11, smooth muscle
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLN phospholamban
PTGIS prostaglandin I2 (prostacyclin) synthase
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
STK39 serine threonine kinase 39
TNS1 tensin 1
TOX3 TOX high mobility group box family member 3
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANXA3 annexin A3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FZD6 frizzled class receptor 6
LAPTM4B lysosomal protein transmembrane 4 beta
LCN2 lipocalin 2
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAGEA12 melanoma antigen family A12
PLAC8 placenta-specific 8
SLPI secretory leukocyte peptidase inhibitor
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
UBE2S ubiquitin-conjugating enzyme E2S