BRD-K77286328_R3904_ASC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

149 genes differentially expressed following the BRD-K77286328_R3904_ASC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ACACB acetyl-CoA carboxylase beta
ADD3 adducin 3 (gamma)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANOS1 anosmin 1
AOC3 amine oxidase, copper containing 3
APOD apolipoprotein D
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ARL4C ADP-ribosylation factor-like 4C
ASPN asporin
ATP9A ATPase, class II, type 9A
C1R complement component 1, r subcomponent
C3 complement component 3
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD93 CD93 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CES1 carboxylesterase 1
CFD complement factor D (adipsin)
CHRDL1 chordin-like 1
CLU clusterin
COL14A1 collagen, type XIV, alpha 1
COL15A1 collagen, type XV, alpha 1
CSF1R colony stimulating factor 1 receptor
CTSF cathepsin F
CX3CL1 chemokine (C-X3-C motif) ligand 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
DCLK1 doublecortin-like kinase 1
DCN decorin
DMD dystrophin
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
FAM198B family with sequence similarity 198, member B
FBLN1 fibulin 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GAS1 growth arrest-specific 1
GHR growth hormone receptor
GPM6B glycoprotein M6B
H1FX H1 histone family, member X
HES1 hes family bHLH transcription factor 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF1 insulin-like growth factor 1 (somatomedin C)
IGHM immunoglobulin heavy constant mu
IL1R1 interleukin 1 receptor, type I
IQGAP1 IQ motif containing GTPase activating protein 1
ITM2A integral membrane protein 2A
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAN1C1 mannosidase, alpha, class 1C, member 1
METTL7A methyltransferase like 7A
MTUS1 microtubule associated tumor suppressor 1
MXRA5 matrix-remodelling associated 5
NBPF10 neuroblastoma breakpoint family, member 10
NCAM1 neural cell adhesion molecule 1
NDRG2 NDRG family member 2
PDGFD platelet derived growth factor D
PDGFRL platelet-derived growth factor receptor-like
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RAB11FIP2 RAB11 family interacting protein 2 (class I)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RTN2 reticulon 2
SFRP4 secreted frizzled-related protein 4
SLCO3A1 solute carrier organic anion transporter family, member 3A1
ST18 suppression of tumorigenicity 18, zinc finger
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SVIL supervillin
SYBU syntabulin (syntaxin-interacting)
TCEA2 transcription elongation factor A (SII), 2
TPP1 tripeptidyl peptidase I
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TSPAN7 tetraspanin 7

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACAT2 acetyl-CoA acetyltransferase 2
ACLY ATP citrate lyase
ALCAM activated leukocyte cell adhesion molecule
ALDOC aldolase C, fructose-bisphosphate
AMD1 adenosylmethionine decarboxylase 1
ATP11B ATPase, class VI, type 11B
BEX1 brain expressed, X-linked 1
BIRC5 baculoviral IAP repeat containing 5
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BOP1 block of proliferation 1
CA12 carbonic anhydrase XII
CCNA2 cyclin A2
CCND1 cyclin D1
CD24 CD24 molecule
CD59 CD59 molecule, complement regulatory protein
CDC20 cell division cycle 20
CDKN3 cyclin-dependent kinase inhibitor 3
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DHCR7 7-dehydrocholesterol reductase
DKK1 dickkopf WNT signaling pathway inhibitor 1
EBNA1BP2 EBNA1 binding protein 2
ELOVL1 ELOVL fatty acid elongase 1
EREG epiregulin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM216A family with sequence similarity 216, member A
FKBP11 FK506 binding protein 11, 19 kDa
FOSL1 FOS-like antigen 1
IDI1 isopentenyl-diphosphate delta isomerase 1
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
LDLR low density lipoprotein receptor
LOX lysyl oxidase
LTF lactotransferrin
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAGED1 melanoma antigen family D1
MELK maternal embryonic leucine zipper kinase
MSMO1 methylsterol monooxygenase 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NFIL3 nuclear factor, interleukin 3 regulated
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPY neuropeptide Y
ODC1 ornithine decarboxylase 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PFKP phosphofructokinase, platelet
PGK1 phosphoglycerate kinase 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PNP purine nucleoside phosphorylase
PTTG1 pituitary tumor-transforming 1
RCAN1 regulator of calcineurin 1
RGS4 regulator of G-protein signaling 4
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPAG4 sperm associated antigen 4
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TAGLN transgelin
TFRC transferrin receptor
THBS1 thrombospondin 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRIP13 thyroid hormone receptor interactor 13
TUBB6 tubulin, beta 6 class V
TYMS thymidylate synthetase
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1
UBE2C ubiquitin-conjugating enzyme E2C
VDAC1 voltage-dependent anion channel 1
WSB2 WD repeat and SOCS box containing 2