BRD-K76908866_CP-724714_SKBR3_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

61 genes differentially expressed following the BRD-K76908866_CP-724714_SKBR3_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGTR1 angiotensin II receptor, type 1
CCNG1 cyclin G1
CCNG2 cyclin G2
CCR7 chemokine (C-C motif) receptor 7
CLDN3 claudin 3
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
ESR1 estrogen receptor 1
GNLY granulysin
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
KDM3A lysine (K)-specific demethylase 3A
MAGED1 melanoma antigen family D1
MBP myelin basic protein
NRCAM neuronal cell adhesion molecule
OPN3 opsin 3
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
RASA4 RAS p21 protein activator 4
RNF19B ring finger protein 19B
RPS4Y1 ribosomal protein S4, Y-linked 1
SEPP1 selenoprotein P, plasma, 1
SPAG4 sperm associated antigen 4
VIM vimentin
WT1 Wilms tumor 1
ZNF217 zinc finger protein 217

decreased expression

Symbol Name
AREG amphiregulin
ARPP19 cAMP-regulated phosphoprotein, 19kDa
CA2 carbonic anhydrase II
CCNE2 cyclin E2
CHN1 chimerin 1
CNN3 calponin 3, acidic
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL9 chemokine (C-X-C motif) ligand 9
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
EIF5A eukaryotic translation initiation factor 5A
EPS8 epidermal growth factor receptor pathway substrate 8
FHL1 four and a half LIM domains 1
H2AFV H2A histone family, member V
IGFBP7 insulin-like growth factor binding protein 7
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KIAA0101 KIAA0101
MED21 mediator complex subunit 21
MME membrane metallo-endopeptidase
MMP12 matrix metallopeptidase 12
MMP3 matrix metallopeptidase 3
MSMO1 methylsterol monooxygenase 1
MT1E metallothionein 1E
NKX3-1 NK3 homeobox 1
NQO1 NAD(P)H dehydrogenase, quinone 1
PAM peptidylglycine alpha-amidating monooxygenase
PHLDA1 pleckstrin homology-like domain, family A, member 1
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
RGCC regulator of cell cycle
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SPRED2 sprouty-related, EVH1 domain containing 2
SULF1 sulfatase 1
TNS3 tensin 3
XIST X inactive specific transcript (non-protein coding)