BRD-K76908866_CP-724714_SKBR3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

107 genes differentially expressed following the BRD-K76908866_CP-724714_SKBR3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
AUTS2 autism susceptibility candidate 2
BTG1 B-cell translocation gene 1, anti-proliferative
C6ORF48 chromosome 6 open reading frame 48
CAPN1 calpain 1, (mu/I) large subunit
CD302 CD302 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CLMN calmin (calponin-like, transmembrane)
CPD carboxypeptidase D
CST3 cystatin C
CST4 cystatin S
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
EXPH5 exophilin 5
EYA2 EYA transcriptional coactivator and phosphatase 2
GLUL glutamate-ammonia ligase
HDAC6 histone deacetylase 6
HECA headcase homolog (Drosophila)
HNMT histamine N-methyltransferase
IDO1 indoleamine 2,3-dioxygenase 1
KAT6B K(lysine) acetyltransferase 6B
KIZ kizuna centrosomal protein
KRT19 keratin 19, type I
LIMK2 LIM domain kinase 2
LOC100272216 uncharacterized LOC100272216
MARCKS myristoylated alanine-rich protein kinase C substrate
METTL7A methyltransferase like 7A
MLPH melanophilin
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MVP major vault protein
OBSL1 obscurin-like 1
PALLD palladin, cytoskeletal associated protein
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFRL platelet-derived growth factor receptor-like
PRUNE prune exopolyphosphatase
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SELENBP1 selenium binding protein 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SIX1 SIX homeobox 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SNAI2 snail family zinc finger 2
TM9SF3 transmembrane 9 superfamily member 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM2 tripartite motif containing 2
TXNIP thioredoxin interacting protein
WFDC2 WAP four-disulfide core domain 2
XBP1 X-box binding protein 1

decreased expression

Symbol Name
AQP1 aquaporin 1 (Colton blood group)
ATAD2 ATPase family, AAA domain containing 2
AURKA aurora kinase A
BIRC5 baculoviral IAP repeat containing 5
CA2 carbonic anhydrase II
CCNA2 cyclin A2
CCND1 cyclin D1
CCND2 cyclin D2
CD52 CD52 molecule
CDC20 cell division cycle 20
CDC25A cell division cycle 25A
CDK1 cyclin-dependent kinase 1
CDKN3 cyclin-dependent kinase inhibitor 3
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CKS2 CDC28 protein kinase regulatory subunit 2
EDNRB endothelin receptor type B
FXYD5 FXYD domain containing ion transport regulator 5
GAL galanin/GMAP prepropeptide
GLIPR1 GLI pathogenesis-related 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HMG20B high mobility group 20B
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IFI6 interferon, alpha-inducible protein 6
JMJD6 jumonji domain containing 6
KIF20A kinesin family member 20A
KRT14 keratin 14, type I
LAGE3 L antigen family, member 3
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
NCAPG non-SMC condensin I complex, subunit G
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NPTX2 neuronal pentraxin II
NPY neuropeptide Y
PBK PDZ binding kinase
PLK1 polo-like kinase 1
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POSTN periostin, osteoblast specific factor
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
RBP1 retinol binding protein 1, cellular
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SPINK1 serine peptidase inhibitor, Kazal type 1
SRM spermidine synthase
TACC3 transforming, acidic coiled-coil containing protein 3
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TNC tenascin C
TSPAN13 tetraspanin 13
TSPYL5 TSPY-like 5
TUBA4A tubulin, alpha 4a
UBE2C ubiquitin-conjugating enzyme E2C
UBE2S ubiquitin-conjugating enzyme E2S
UPP1 uridine phosphorylase 1
VIM vimentin
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)