BRD-K76810206_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K76810206_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACLY ATP citrate lyase
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CRISP3 cysteine-rich secretory protein 3
CST6 cystatin E/M
CXCL5 chemokine (C-X-C motif) ligand 5
DPP4 dipeptidyl-peptidase 4
FADS1 fatty acid desaturase 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HSPA1A heat shock 70kDa protein 1A
IDI1 isopentenyl-diphosphate delta isomerase 1
IL1R2 interleukin 1 receptor, type II
INSIG1 insulin induced gene 1
KRT6A keratin 6A, type II
LDLR low density lipoprotein receptor
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
MSMO1 methylsterol monooxygenase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
QPCT glutaminyl-peptide cyclotransferase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCN3A sodium channel, voltage gated, type III alpha subunit
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SQLE squalene epoxidase
TACSTD2 tumor-associated calcium signal transducer 2
TXNDC9 thioredoxin domain containing 9
VCAN versican
XBP1 X-box binding protein 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
C1QA complement component 1, q subcomponent, A chain
CDC42 cell division cycle 42
CPE carboxypeptidase E
DKK3 dickkopf WNT signaling pathway inhibitor 3
EIF5A eukaryotic translation initiation factor 5A
FRZB frizzled-related protein
GATAD1 GATA zinc finger domain containing 1
GLUL glutamate-ammonia ligase
GPM6A glycoprotein M6A
GPNMB glycoprotein (transmembrane) nmb
HNRNPL heterogeneous nuclear ribonucleoprotein L
IFRD2 interferon-related developmental regulator 2
MZT2B mitotic spindle organizing protein 2B
NPIPB3 nuclear pore complex interacting protein family, member B3
PEG3 paternally expressed 3
PKN2 protein kinase N2
SCAND1 SCAN domain containing 1
SELENBP1 selenium binding protein 1
SET SET nuclear proto-oncogene
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
VEGFA vascular endothelial growth factor A
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon