BRD-K76694128_DCC-2036_MCF7_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

102 genes differentially expressed following the BRD-K76694128_DCC-2036_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG2 adhesion G protein-coupled receptor G2
AEBP1 AE binding protein 1
ANXA3 annexin A3
AOX1 aldehyde oxidase 1
APOD apolipoprotein D
AREG amphiregulin
ASPH aspartate beta-hydroxylase
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CAV1 caveolin 1, caveolae protein, 22kDa
CCNA1 cyclin A1
CD99 CD99 molecule
CFB complement factor B
CKLF chemokine-like factor
COL11A1 collagen, type XI, alpha 1
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CTGF connective tissue growth factor
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
EGR3 early growth response 3
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FABP4 fatty acid binding protein 4, adipocyte
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
GREM1 gremlin 1, DAN family BMP antagonist
HACD2 3-hydroxyacyl-CoA dehydratase 2
HBEGF heparin-binding EGF-like growth factor
KRT23 keratin 23, type I
LCN2 lipocalin 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NLGN4X neuroligin 4, X-linked
NNMT nicotinamide N-methyltransferase
NRIP1 nuclear receptor interacting protein 1
NT5E 5'-nucleotidase, ecto (CD73)
OPN3 opsin 3
OSBPL10 oxysterol binding protein-like 10
PDE4B phosphodiesterase 4B, cAMP-specific
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLK2 polo-like kinase 2
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A
PRR7 proline rich 7 (synaptic)
PRSS3 protease, serine, 3
PYGL phosphorylase, glycogen, liver
RND3 Rho family GTPase 3
RUNX1 runt-related transcription factor 1
S100A10 S100 calcium binding protein A10
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SMAD3 SMAD family member 3
SORBS1 sorbin and SH3 domain containing 1
SOX9 SRY (sex determining region Y)-box 9
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
VDAC1 voltage-dependent anion channel 1
WWTR1 WW domain containing transcription regulator 1

decreased expression

Symbol Name
ARMCX3 armadillo repeat containing, X-linked 3
ARMCX6 armadillo repeat containing, X-linked 6
ARMT1 acidic residue methyltransferase 1
ATF5 activating transcription factor 5
ATHL1 ATH1, acid trehalase-like 1 (yeast)
C8ORF4 chromosome 8 open reading frame 4
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CAPN1 calpain 1, (mu/I) large subunit
CDC42 cell division cycle 42
CHGB chromogranin B
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CKB creatine kinase, brain
CXCL13 chemokine (C-X-C motif) ligand 13
DMBT1 deleted in malignant brain tumors 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
GNAS GNAS complex locus
GPER1 G protein-coupled estrogen receptor 1
GSTA4 glutathione S-transferase alpha 4
HEBP1 heme binding protein 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ITM2A integral membrane protein 2A
LAMP3 lysosomal-associated membrane protein 3
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAL mal, T-cell differentiation protein
METTL7A methyltransferase like 7A
PEG3 paternally expressed 3
PFN2 profilin 2
POU2AF1 POU class 2 associating factor 1
PPAP2B phosphatidic acid phosphatase type 2B
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SFTPC surfactant protein C
SFTPD surfactant protein D
SPEN spen family transcriptional repressor
TBX3 T-box 3
TSC22D3 TSC22 domain family, member 3
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17