BRD-K76694128_DCC-2036_HCC515_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

113 genes differentially expressed following the BRD-K76694128_DCC-2036_HCC515_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM19 ADAM metallopeptidase domain 19
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AMIGO2 adhesion molecule with Ig-like domain 2
ANK2 ankyrin 2, neuronal
ANXA5 annexin A5
ARHGAP29 Rho GTPase activating protein 29
BASP1 brain abundant, membrane attached signal protein 1
BDNF brain-derived neurotrophic factor
CAPN6 calpain 6
CD44 CD44 molecule (Indian blood group)
CDA cytidine deaminase
CECR1 cat eye syndrome chromosome region, candidate 1
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL13 chemokine (C-X-C motif) ligand 13
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DUSP6 dual specificity phosphatase 6
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFNB2 ephrin-B2
EGR3 early growth response 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EREG epiregulin
FABP4 fatty acid binding protein 4, adipocyte
FAM198B family with sequence similarity 198, member B
FBN2 fibrillin 2
FBP1 fructose-1,6-bisphosphatase 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
GALC galactosylceramidase
HAPLN1 hyaluronan and proteoglycan link protein 1
HOPX HOP homeobox
ITM2A integral membrane protein 2A
JUN jun proto-oncogene
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF4 Kruppel-like factor 4 (gut)
LAMP5 lysosomal-associated membrane protein family, member 5
MNDA myeloid cell nuclear differentiation antigen
MYBPC1 myosin binding protein C, slow type
NAV3 neuron navigator 3
NEFL neurofilament, light polypeptide
NR2F2 nuclear receptor subfamily 2, group F, member 2
OGN osteoglycin
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLEK2 pleckstrin 2
POPDC3 popeye domain containing 3
PTHLH parathyroid hormone-like hormone
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RGS2 regulator of G-protein signaling 2
S100A12 S100 calcium binding protein A12
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SOX9 SRY (sex determining region Y)-box 9
SPRY2 sprouty homolog 2 (Drosophila)
STX1A syntaxin 1A (brain)
SYT1 synaptotagmin I
THBS4 thrombospondin 4
WWTR1 WW domain containing transcription regulator 1

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADD3 adducin 3 (gamma)
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
AQP3 aquaporin 3 (Gill blood group)
C2CD5 C2 calcium-dependent domain containing 5
C3 complement component 3
C5 complement component 5
CAPN1 calpain 1, (mu/I) large subunit
CCNB2 cyclin B2
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDC45 cell division cycle 45
CFB complement factor B
CLTB clathrin, light chain B
CP ceruloplasmin (ferroxidase)
CPA3 carboxypeptidase A3 (mast cell)
CPB1 carboxypeptidase B1 (tissue)
CXADR coxsackie virus and adenovirus receptor
CYB5A cytochrome b5 type A (microsomal)
DNTT DNA nucleotidylexotransferase
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FAM69A family with sequence similarity 69, member A
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
GCLC glutamate-cysteine ligase, catalytic subunit
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
HLA-DRA major histocompatibility complex, class II, DR alpha
IGL immunoglobulin lambda locus
JUP junction plakoglobin
LCN2 lipocalin 2
LEF1 lymphoid enhancer-binding factor 1
LPAR6 lysophosphatidic acid receptor 6
LTBP1 latent transforming growth factor beta binding protein 1
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MMD monocyte to macrophage differentiation-associated
MUC1 mucin 1, cell surface associated
PRAME preferentially expressed antigen in melanoma
RPS4Y1 ribosomal protein S4, Y-linked 1
SEPP1 selenoprotein P, plasma, 1
SLPI secretory leukocyte peptidase inhibitor
SPINK1 serine peptidase inhibitor, Kazal type 1
SQSTM1 sequestosome 1
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM106C transmembrane protein 106C
TRIM29 tripartite motif containing 29
TSC22D3 TSC22 domain family, member 3
VCAM1 vascular cell adhesion molecule 1
ZNF274 zinc finger protein 274
ZSCAN18 zinc finger and SCAN domain containing 18