BRD-K76691125_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

36 genes differentially expressed following the BRD-K76691125_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CHPT1 choline phosphotransferase 1
CYBA cytochrome b-245, alpha polypeptide
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
GREB1 growth regulation by estrogen in breast cancer 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA1A heat shock 70kDa protein 1A
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
LAMP5 lysosomal-associated membrane protein family, member 5
LEF1 lymphoid enhancer-binding factor 1
LXN latexin
NR2F2 nuclear receptor subfamily 2, group F, member 2
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUP98 nucleoporin 98kDa
PLXNC1 plexin C1
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SMS spermine synthase

decreased expression

Symbol Name
CD24 CD24 molecule
CP ceruloplasmin (ferroxidase)
CPA3 carboxypeptidase A3 (mast cell)
GJA1 gap junction protein, alpha 1, 43kDa
GPNMB glycoprotein (transmembrane) nmb
GPX2 glutathione peroxidase 2
MTCL1 microtubule crosslinking factor 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PTHLH parathyroid hormone-like hormone
S100A8 S100 calcium binding protein A8
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
THY1 Thy-1 cell surface antigen
TMEM176A transmembrane protein 176A
TMEM176B transmembrane protein 176B
ZNF395 zinc finger protein 395