BRD-K76401790_JNK-IN-5A_HT29_24_h_10_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

125 genes differentially expressed following the BRD-K76401790_JNK-IN-5A_HT29_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANOS1 anosmin 1
ANXA3 annexin A3
AURKA aurora kinase A
BEX1 brain expressed, X-linked 1
C6ORF62 chromosome 6 open reading frame 62
C7 complement component 7
CCND1 cyclin D1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CLEC2B C-type lectin domain family 2, member B
CLIC4 chloride intracellular channel 4
COL18A1 collagen, type XVIII, alpha 1
DKK3 dickkopf WNT signaling pathway inhibitor 3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FBN2 fibrillin 2
FHL2 four and a half LIM domains 2
FLRT2 fibronectin leucine rich transmembrane protein 2
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
GOLM1 golgi membrane protein 1
HDAC6 histone deacetylase 6
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP7 insulin-like growth factor binding protein 7
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
LAMA3 laminin, alpha 3
LRP4 low density lipoprotein receptor-related protein 4
MACF1 microtubule-actin crosslinking factor 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
NMU neuromedin U
NRCAM neuronal cell adhesion molecule
PEG3 paternally expressed 3
PLK1 polo-like kinase 1
PLS3 plastin 3
PRSS21 protease, serine, 21 (testisin)
RPS11 ribosomal protein S11
RPS5 ribosomal protein S5
SDC2 syndecan 2
SFN stratifin
SPTBN1 spectrin, beta, non-erythrocytic 1
TBX2 T-box 2
TGFB3 transforming growth factor, beta 3
TPBG trophoblast glycoprotein
TRPS1 trichorhinophalangeal syndrome I
UBE2S ubiquitin-conjugating enzyme E2S
WDR7 WD repeat domain 7

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
AQP3 aquaporin 3 (Gill blood group)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BET1 Bet1 golgi vesicular membrane trafficking protein
BHLHE41 basic helix-loop-helix family, member e41
BIRC3 baculoviral IAP repeat containing 3
CCL20 chemokine (C-C motif) ligand 20
CD200 CD200 molecule
CDK1 cyclin-dependent kinase 1
CHEK2 checkpoint kinase 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CPOX coproporphyrinogen oxidase
CXCL12 chemokine (C-X-C motif) ligand 12
CYB5A cytochrome b5 type A (microsomal)
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUSP6 dual specificity phosphatase 6
ECHDC2 enoyl CoA hydratase domain containing 2
ELP5 elongator acetyltransferase complex subunit 5
FAM120A family with sequence similarity 120A
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GDF15 growth differentiation factor 15
GEM GTP binding protein overexpressed in skeletal muscle
GINS1 GINS complex subunit 1 (Psf1 homolog)
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HBB hemoglobin, beta
HES1 hes family bHLH transcription factor 1
HILPDA hypoxia inducible lipid droplet-associated
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
KRT23 keratin 23, type I
LGALS3 lectin, galactoside-binding, soluble, 3
LOC100505650 uncharacterized LOC100505650
MLF1 myeloid leukemia factor 1
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MTSS1 metastasis suppressor 1
NET1 neuroepithelial cell transforming 1
NUSAP1 nucleolar and spindle associated protein 1
PEG10 paternally expressed 10
PLAT plasminogen activator, tissue
PRKCD protein kinase C, delta
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RNMT RNA (guanine-7-) methyltransferase
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RRM2 ribonucleotide reductase M2
SEPT2 septin 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SMCO4 single-pass membrane protein with coiled-coil domains 4
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRGN serglycin
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI2 tissue factor pathway inhibitor 2
TMX4 thioredoxin-related transmembrane protein 4
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP2A topoisomerase (DNA) II alpha 170kDa
TPPP3 tubulin polymerization-promoting protein family member 3
TRIB1 tribbles pseudokinase 1
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VCAM1 vascular cell adhesion molecule 1
ZFAND5 zinc finger, AN1-type domain 5
ZFP36L1 ZFP36 ring finger protein-like 1