BRD-K76401790_JNK-IN-5A_HT29_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

149 genes differentially expressed following the BRD-K76401790_JNK-IN-5A_HT29_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABLIM1 actin binding LIM protein 1
ACSL1 acyl-CoA synthetase long-chain family member 1
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AREG amphiregulin
AURKA aurora kinase A
BASP1 brain abundant, membrane attached signal protein 1
CCND2 cyclin D2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CELF2 CUGBP, Elav-like family member 2
COL18A1 collagen, type XVIII, alpha 1
CST7 cystatin F (leukocystatin)
CTSL cathepsin L
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
FLRT2 fibronectin leucine rich transmembrane protein 2
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
GJA1 gap junction protein, alpha 1, 43kDa
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HP haptoglobin
HSPB8 heat shock 22kDa protein 8
IGFBP7 insulin-like growth factor binding protein 7
IRS2 insulin receptor substrate 2
ITGB4 integrin, beta 4
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KIF14 kinesin family member 14
KIF5B kinesin family member 5B
KLK10 kallikrein-related peptidase 10
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MT1E metallothionein 1E
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NNMT nicotinamide N-methyltransferase
NPTX2 neuronal pentraxin II
PAWR PRKC, apoptosis, WT1, regulator
PDLIM3 PDZ and LIM domain 3
PLK1 polo-like kinase 1
PLS3 plastin 3
PRDX2 peroxiredoxin 2
REEP5 receptor accessory protein 5
SERINC5 serine incorporator 5
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SORD sorbitol dehydrogenase
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPON1 spondin 1, extracellular matrix protein
STAR steroidogenic acute regulatory protein
SYBU syntabulin (syntaxin-interacting)
TERT telomerase reverse transcriptase
THBS1 thrombospondin 1
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
TIMP1 TIMP metallopeptidase inhibitor 1
VDAC1 voltage-dependent anion channel 1
WT1 Wilms tumor 1
ZMYM2 zinc finger, MYM-type 2

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ANO3 anoctamin 3
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ATF3 activating transcription factor 3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BMP2 bone morphogenetic protein 2
CA12 carbonic anhydrase XII
CCL20 chemokine (C-C motif) ligand 20
CCNG2 cyclin G2
CD58 CD58 molecule
CDK1 cyclin-dependent kinase 1
CHEK2 checkpoint kinase 2
CHRDL1 chordin-like 1
CLMN calmin (calponin-like, transmembrane)
CPM carboxypeptidase M
CTSK cathepsin K
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL5 chemokine (C-X-C motif) ligand 5
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
EAF2 ELL associated factor 2
EFNB2 ephrin-B2
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EMX2 empty spiracles homeobox 2
FABP7 fatty acid binding protein 7, brain
FRZB frizzled-related protein
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLS glutaminase
HACD2 3-hydroxyacyl-CoA dehydratase 2
HBB hemoglobin, beta
HILPDA hypoxia inducible lipid droplet-associated
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGB2 high mobility group box 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
KRT19 keratin 19, type I
KRT23 keratin 23, type I
LAMP5 lysosomal-associated membrane protein family, member 5
LPL lipoprotein lipase
LTF lactotransferrin
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MELK maternal embryonic leucine zipper kinase
MEOX2 mesenchyme homeobox 2
MMP7 matrix metallopeptidase 7
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NCF2 neutrophil cytosolic factor 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NET1 neuroepithelial cell transforming 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NREP neuronal regeneration related protein
OLFML2A olfactomedin-like 2A
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PAIP1 poly(A) binding protein interacting protein 1
PEG10 paternally expressed 10
PENK proenkephalin
PLBD1 phospholipase B domain containing 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLIN2 perilipin 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKCD protein kinase C, delta
RCAN1 regulator of calcineurin 1
RGS2 regulator of G-protein signaling 2
RND3 Rho family GTPase 3
RNMT RNA (guanine-7-) methyltransferase
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SLAMF1 signaling lymphocytic activation molecule family member 1
SV2C synaptic vesicle glycoprotein 2C
TAC1 tachykinin, precursor 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TMED10 transmembrane emp24-like trafficking protein 10 (yeast)
TMEM45A transmembrane protein 45A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
TOP2A topoisomerase (DNA) II alpha 170kDa
TXNIP thioredoxin interacting protein
TYMS thymidylate synthetase
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VCAM1 vascular cell adhesion molecule 1
WEE1 WEE1 G2 checkpoint kinase
ZSCAN18 zinc finger and SCAN domain containing 18