BRD-K76401790_JNK-IN-5A_HCC515_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K76401790_JNK-IN-5A_HCC515_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
AURKA aurora kinase A
BIRC5 baculoviral IAP repeat containing 5
CCNB2 cyclin B2
CENPF centromere protein F, 350/400kDa
CKB creatine kinase, brain
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
FOSL1 FOS-like antigen 1
IL13RA2 interleukin 13 receptor, alpha 2
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
METTL7A methyltransferase like 7A
NDC80 NDC80 kinetochore complex component
PCP4 Purkinje cell protein 4
PLK1 polo-like kinase 1
PODXL podocalyxin-like
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PSRC1 proline/serine-rich coiled-coil 1
RBP1 retinol binding protein 1, cellular
TNC tenascin C
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZNF432 zinc finger protein 432

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BASP1 brain abundant, membrane attached signal protein 1
BEX1 brain expressed, X-linked 1
C10ORF10 chromosome 10 open reading frame 10
C1S complement component 1, s subcomponent
C3 complement component 3
C8ORF4 chromosome 8 open reading frame 4
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFB complement factor B
CLU clusterin
COASY CoA synthase
CXCL5 chemokine (C-X-C motif) ligand 5
CYB5A cytochrome b5 type A (microsomal)
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
EIF5A eukaryotic translation initiation factor 5A
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGG fibrinogen gamma chain
GATA6 GATA binding protein 6
GJA1 gap junction protein, alpha 1, 43kDa
GPATCH8 G patch domain containing 8
GPRC5A G protein-coupled receptor, class C, group 5, member A
HILPDA hypoxia inducible lipid droplet-associated
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFITM1 interferon induced transmembrane protein 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL32 interleukin 32
KRT19 keratin 19, type I
MFSD10 major facilitator superfamily domain containing 10
MYC v-myc avian myelocytomatosis viral oncogene homolog
NID2 nidogen 2 (osteonidogen)
PLAGL1 pleiomorphic adenoma gene-like 1
PPIC peptidylprolyl isomerase C (cyclophilin C)
PPIF peptidylprolyl isomerase F
RNASE4 ribonuclease, RNase A family, 4
S100P S100 calcium binding protein P
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
TBC1D4 TBC1 domain family, member 4
TM4SF1 transmembrane 4 L six family member 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TPM2 tropomyosin 2 (beta)
UBE3C ubiquitin protein ligase E3C
UGDH UDP-glucose 6-dehydrogenase
XIST X inactive specific transcript (non-protein coding)