BRD-K76401790_JNK-IN-5A_HA1E_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K76401790_JNK-IN-5A_HA1E_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C1QA complement component 1, q subcomponent, A chain
CCNA1 cyclin A1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
EREG epiregulin
FOSL1 FOS-like antigen 1
H1F0 H1 histone family, member 0
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BK histone cluster 1, H2bk
ITGA6 integrin, alpha 6
LMO3 LIM domain only 3 (rhombotin-like 2)
NFIB nuclear factor I/B
SEPP1 selenoprotein P, plasma, 1
TWF1 twinfilin actin binding protein 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2

decreased expression

Symbol Name
ANXA6 annexin A6
AQP3 aquaporin 3 (Gill blood group)
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA12 carbonic anhydrase XII
CCDC92 coiled-coil domain containing 92
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
COL1A2 collagen, type I, alpha 2
CXCL12 chemokine (C-X-C motif) ligand 12
DACT1 dishevelled-binding antagonist of beta-catenin 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
ECM1 extracellular matrix protein 1
EPHA3 EPH receptor A3
FAM129A family with sequence similarity 129, member A
FSTL1 follistatin-like 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KRT13 keratin 13, type I
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRRC17 leucine rich repeat containing 17
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MEIS2 Meis homeobox 2
NDN necdin, melanoma antigen (MAGE) family member
NREP neuronal regeneration related protein
OLFML3 olfactomedin-like 3
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PGM1 phosphoglucomutase 1
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PROM1 prominin 1
PTGIS prostaglandin I2 (prostacyclin) synthase
QPRT quinolinate phosphoribosyltransferase
RAB25 RAB25, member RAS oncogene family
RNASE4 ribonuclease, RNase A family, 4
S100A7 S100 calcium binding protein A7
S100P S100 calcium binding protein P
SEPT6 septin 6
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STK39 serine threonine kinase 39
TFF1 trefoil factor 1
TMEM97 transmembrane protein 97
UBE2A ubiquitin-conjugating enzyme E2A
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)