BRD-K76401790_JNK-IN-5A_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K76401790_JNK-IN-5A_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BCAM basal cell adhesion molecule (Lutheran blood group)
CCL2 chemokine (C-C motif) ligand 2
CDA cytidine deaminase
CXCL3 chemokine (C-X-C motif) ligand 3
CYR61 cysteine-rich, angiogenic inducer, 61
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FNBP1 formin binding protein 1
FOSL1 FOS-like antigen 1
FSTL1 follistatin-like 1
HIST1H2BC histone cluster 1, H2bc
HIST1H2BG histone cluster 1, H2bg
HOXB6 homeobox B6
LDLR low density lipoprotein receptor
MAGEA6 melanoma antigen family A6
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
NTAN1 N-terminal asparagine amidase
PHLDA1 pleckstrin homology-like domain, family A, member 1
S100A12 S100 calcium binding protein A12
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SQRDL sulfide quinone reductase-like (yeast)
TNIP1 TNFAIP3 interacting protein 1
TSPAN4 tetraspanin 4

decreased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ASPN asporin
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCNA1 cyclin A1
CDCA4 cell division cycle associated 4
CDK1 cyclin-dependent kinase 1
CP ceruloplasmin (ferroxidase)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CXCL10 chemokine (C-X-C motif) ligand 10
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EIF5A eukaryotic translation initiation factor 5A
GINS1 GINS complex subunit 1 (Psf1 homolog)
GPX2 glutathione peroxidase 2
HES1 hes family bHLH transcription factor 1
HILPDA hypoxia inducible lipid droplet-associated
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
MDK midkine (neurite growth-promoting factor 2)
MGP matrix Gla protein
MXRA5 matrix-remodelling associated 5
NID2 nidogen 2 (osteonidogen)
NOTCH3 notch 3
NQO1 NAD(P)H dehydrogenase, quinone 1
PCP4 Purkinje cell protein 4
RAP1GAP RAP1 GTPase activating protein
RNASE4 ribonuclease, RNase A family, 4
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SLC16A4 solute carrier family 16, member 4
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAT1 signal transducer and activator of transcription 1, 91kDa
SULF1 sulfatase 1
TOP2A topoisomerase (DNA) II alpha 170kDa
TOPBP1 topoisomerase (DNA) II binding protein 1
TPD52L1 tumor protein D52-like 1
UBE2A ubiquitin-conjugating enzyme E2A
UBE2C ubiquitin-conjugating enzyme E2C
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28