BRD-K76401790_JNK-IN-5A_A549_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K76401790_JNK-IN-5A_A549_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
CAV2 caveolin 2
CYR61 cysteine-rich, angiogenic inducer, 61
EGR1 early growth response 1
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HMOX1 heme oxygenase 1
IER5 immediate early response 5
KLF6 Kruppel-like factor 6
LAMP3 lysosomal-associated membrane protein 3
MAGEA1 melanoma antigen family A1
MAGEA12 melanoma antigen family A12
NPR3 natriuretic peptide receptor 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SESN1 sestrin 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ATAD2 ATPase family, AAA domain containing 2
CDK1 cyclin-dependent kinase 1
CEMIP cell migration inducing protein, hyaluronan binding
CYBA cytochrome b-245, alpha polypeptide
HES1 hes family bHLH transcription factor 1
IGFBP5 insulin-like growth factor binding protein 5
LXN latexin
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MELK maternal embryonic leucine zipper kinase
NUSAP1 nucleolar and spindle associated protein 1
RAD51AP1 RAD51 associated protein 1
RFC2 replication factor C (activator 1) 2, 40kDa
RRM2 ribonucleotide reductase M2
S100A8 S100 calcium binding protein A8
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2C ubiquitin-conjugating enzyme E2C