BRD-K76401790_JNK-IN-5A_A375_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

104 genes differentially expressed following the BRD-K76401790_JNK-IN-5A_A375_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM2 absent in melanoma 2
ATF3 activating transcription factor 3
BTG2 BTG family, member 2
CCNA1 cyclin A1
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLGN calmegin
CYR61 cysteine-rich, angiogenic inducer, 61
DDB2 damage-specific DNA binding protein 2, 48kDa
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DUSP14 dual specificity phosphatase 14
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNB2 ephrin-B2
EGR1 early growth response 1
FDXR ferredoxin reductase
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GDF15 growth differentiation factor 15
GLIPR1 GLI pathogenesis-related 1
GPNMB glycoprotein (transmembrane) nmb
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BH histone cluster 1, H2bh
HIST1H2BK histone cluster 1, H2bk
HMOX1 heme oxygenase 1
HSPA4L heat shock 70kDa protein 4-like
MFAP3L microfibrillar-associated protein 3-like
MYOF myoferlin
NUPR1 nuclear protein, transcriptional regulator, 1
PCLO piccolo presynaptic cytomatrix protein
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RND3 Rho family GTPase 3
SESN1 sestrin 1
SLC43A3 solute carrier family 43, member 3
VAMP8 vesicle-associated membrane protein 8

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
ANXA6 annexin A6
AQP1 aquaporin 1 (Colton blood group)
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40
ASPH aspartate beta-hydroxylase
C1ORF106 chromosome 1 open reading frame 106
CA1 carbonic anhydrase I
CA12 carbonic anhydrase XII
CAT catalase
CBR3 carbonyl reductase 3
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD99 CD99 molecule
CDK1 cyclin-dependent kinase 1
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
CSTA cystatin A (stefin A)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL5 chemokine (C-X-C motif) ligand 5
DCN decorin
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL2 dihydropyrimidinase-like 2
DPYSL3 dihydropyrimidinase-like 3
F3 coagulation factor III (thromboplastin, tissue factor)
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGG fibrinogen gamma chain
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GNAS GNAS complex locus
HOPX HOP homeobox
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IGFBP7 insulin-like growth factor binding protein 7
IGHD immunoglobulin heavy constant delta
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
LMCD1 LIM and cysteine-rich domains 1
LRRC17 leucine rich repeat containing 17
LTF lactotransferrin
MAP2K6 mitogen-activated protein kinase kinase 6
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MUC5B mucin 5B, oligomeric mucus/gel-forming
NDRG2 NDRG family member 2
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NREP neuronal regeneration related protein
PCOLCE procollagen C-endopeptidase enhancer
PGM1 phosphoglucomutase 1
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SEPP1 selenoprotein P, plasma, 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPRR1A small proline-rich protein 1A
SPTSSA serine palmitoyltransferase, small subunit A
TCF4 transcription factor 4
THBS2 thrombospondin 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2C ubiquitin-conjugating enzyme E2C
VCAN versican
VDAC1 voltage-dependent anion channel 1